2025年3月30日 · This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA …

2019年2月11日 · Mutations in the MAPT gene that encodes tau can cause frontotemporal dementia with parkinsonism linked to chromosome 17 (FTDP-17), providing the clearest …

In humans, the MAPT gene for encoding tau protein is located on chromosome 17q21, containing 16 exons. [30] The major tau protein in the human brain is encoded by 11 exons. Exons 2, 3 …

The MAPT gene provides instructions for making a protein called tau. This protein is found throughout the nervous system, including in nerve cells (neurons) in the brain.

2000年11月7日 · MAPT -FTD is a progressive disorder that commonly ends with a relatively global dementia in which some affected individuals become mute. Progression of motor …

2025年3月27日 · This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA …

2015年9月15日 · Microtubule-associated protein tau (MAPT) is a gene responsible for encoding tau protein, which is tightly implicated in keeping the function of microtubules and axonal …

MAPT (micro-tubule associated protein) encodes tau and resides within a ~900 kilobase (kb) inversion polymorphism (reviewed [1]) that generates a ~1.3 megabase (Mb) region of linkage …

2012年5月8日 · This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA …

2015年9月12日 · Microtubule-associated protein tau (MAPT) is a gene responsible for encoding tau protein, which is tightly implicated in keeping the function of microtubules and axonal …