NOX4 - Wikipedia
NADPH oxidase 4 is an enzyme that in humans is encoded by the NOX4 gene, and is a member of the NOX family of NADPH oxidases. [5]
NDT | NADPH 氧化酶 4 在肾脏和心血管系统中的潜在获益与危害
2019年8月9日 · nox4 是一种跨膜蛋白，与 nox2 的同源性为 38%，但已鉴定出几种剪接变异体。 NOX4 与其他 NOX 亚型的重要区别在于，NOX4 具有组成性活性，主要产生 H2O2 而不是 O2·-。
NADPH oxidase 4 (Nox4) is a major source of oxidative stress in …
2010年8月31日 · NAD(P)H oxidases (Noxs) produce O(2)(-) and play an important role in cardiovascular pathophysiology. The Nox4 isoform is expressed primarily in the mitochondria …
NADPH 氧化酶 (NOX) 的发现、分子机制、生理学和病理学概述
2024年6月6日 · 烟酰胺腺嘌呤二核苷酸磷酸氧化酶 (NOX) 是一种产生活性氧 (ROS) 的酶，最初在吞噬细胞膜中被发现。 它的主要作用是在免疫防御中，通过产生 ROS 来破坏病原体。 NOX …
NOX4 Gene - GeneCards | NOX4 Protein | NOX4 Antibody
2024年12月25日 · NOX4 (NADPH Oxidase 4) is a Protein Coding gene. Diseases associated with NOX4 include Ureteral Obstruction and Pulmonary Hypertension. Among its related pathways …
Nox4: A Hydrogen Peroxide-Generating Oxygen Sensor - PMC
Critically, Nox4 has an unusually high K m for oxygen (∼18%), similar to the values of known oxygen-sensing enzymes, compared with a K m of 2–3% for Nox2, the phagocyte NADPH …
The human Nox4: gene, structure, physiological function and
This article explores the experimental studies related to the gene, structure, physiological function and pathological significance of Nox4. As Nox4 might serve as a potential target for the …
Nox4: From Discovery to Pathophysiology | SpringerLink
2023年6月23日 · Nox4, originally termed Renox, was discovered in 2000. Since that time, our understanding of its structure and function has expanded enormously. Nox4 is ubiquitously …
NOX-4型NADPH氧化酶在肺部疾病中的研究进展 - 国际呼吸杂志
烟酰胺腺嘌呤二核苷酸磷酸氧化酶4 (NOX-4)主要经介导活性氧簇 (ROS)的产生发挥生物学作用，参与自身稳态维持、炎症免疫反应、组织修复、肿瘤恶性转化等，异常NOX-4导致的氧化应 …
NADPH 氧化酶 4（NOX4）基因 | MCE - MCE-生物活性分子大师
该基因编码 NOX 酶家族的一个成员，其作为 NADPH 氧化酶复合物的催化亚基发挥作用。 编码的蛋白质定位于非吞噬细胞，在那里它充当氧传感器并催化分子氧还原为各种活性氧 (ROS) 。 …