These diverticula make their appearance before the closure of the anterior end of the neural tube; [1] [2] after the closure of the tube around the 4th week of development, they are known as the …

The first morphological sign of eye morphogenesis is evagination of the optic vesicles, which occurs in the ventral forebrain during the final stages of neural tube formation . Detailed …

The optic vesicle is defined as an evagination from the diencephalon that, upon contact with the surface ectoderm, develops into presumptive retinal pigment epithelium, neural retina, and …

2023年3月27日 · The optic vesicles are hollow diverticula that protrude through the surrounding mesenchyme towards the surface ectoderm. This protrusion not only leads to the eventual …

At E8.5–9.0 of mouse development, the walls of the diencephalon evaginate (the optic vesicles) and come into close contact with the surface ectoderm (Fig. 1D) where the lens placode is …

Organogenesis of the eye is a multistep process that starts with the formation of optic vesicles followed by invagination of the distal domain of the vesicles and the overlying lens placode …

通过修改将iPSCs转化为神经组织的培养条件，研究人员成功地在大脑类器官中诱导出了双侧对称视杯 （optic cup，视觉系统的组成部分之一）， 并发现这种结构可以感知光线，同时将信号 …

2021年10月7日 · During embryogenesis, optic vesicles develop from the diencephalon via a multistep process of organogenesis. Using induced pluripotent stem cell (iPSC)-derived …

2007年5月1日 · Optic vesicle formation, transformation into an optic cup and integration with neighboring tissues are essential for normal eye formation, and involve the coordinated …

First, an outpocketing of the neural tube occurs, creating optic vesicles. Development of the optic vesicles starts in the three-week embryo from a progressively deepening groove in the neural …