PDK2 - Wikipedia
Pyruvate dehydrogenase kinase isoform 2 (PDK2) also known as pyruvate dehydrogenase lipoamide kinase isozyme 2, mitochondrial is an enzyme that in humans is encoded by the …
PDK2 Gene - GeneCards | PDK2 Protein | PDK2 Antibody
2024年12月25日 · PDK2 (Pyruvate Dehydrogenase Kinase 2) is a Protein Coding gene. Diseases associated with PDK2 include Pyruvate Dehydrogenase E3-Binding Protein Deficiency and …
IF 13.437｜江沛教授团队揭示PDK2在调节大脑能量代谢和抑郁症 …
2023年5月，山东第一医科大学附属济宁市第一人民医院江沛团队在Molecular Psychiatry（IF 13.437）上在线发表了题为“Targeting PDK2 rescues stress-induced impaired brain energy …
丙酮酸脱氢酶激酶 2（PDK2）基因 | MCE - MCE-生物活性 ...
该基因编码丙酮酸脱氢酶激酶家族的成员。 编码的蛋白质磷酸化丙酮酸脱氢酶，下调线粒体丙酮酸脱氢酶复合物的活性。 该基因的过度表达可能在癌症和糖尿病中发挥作用。 已经观察到该基 …
Pyruvate dehydrogenase kinases (PDKs): an overview toward …
PDK2 is a key regulator of glycolysis and oxidative phosphorylation, and its expression is increased in a variety of tumors. The metabolism of glutamine and glucose is recognized as a …
PDK2 pyruvate dehydrogenase kinase 2 [ (human)] - National …
we identified PDK2 as the most up-regulated kinase encoding gene in Cisplatin resistant lung adenocarcinoma and PDK2-dependent Cisplatin-resistance promotes tumour growth of lung …
丙酮酸脱氢酶的结构、功能与相关疾病 - 知乎 - 知乎专栏
实验表明，靶向抑制PDK可逆转肿瘤细胞中的Warburg效应，降低肿瘤微环境中的乳酸浓度，增加线粒体产生的活性氧（ROS）的产生，降低HIF1α的表达，并诱导caspase介导的肿瘤细胞选 …
Pdk2 pyruvate dehydrogenase kinase, isoenzyme 2 [ (house …
2025年2月8日 · Enables pyruvate dehydrogenase (acetyl-transferring) kinase activity. Involved in several processes, including glucose homeostasis; insulin receptor signaling pathway; and …
张金兰研究员与蒋建东院士团队揭示灯盏乙素靶向调控脑组织线粒体PDK2 …
2023年10月9日 · 该研究首次发现了灯盏乙素靶向脑组织线粒体丙酮酸脱氢酶激酶-丙酮酸脱氢酶复合物轴（PDK2-PDC）调控线粒体有氧代谢，能够挽救受损的线粒体，进而发挥神经细胞保护 …
丙酮酸脱氢酶激酶 2 | Pyruvate dehydrogenase kinase 2 (PDK2)
丙酮酸脱氢酶激酶 2 (pdk2) 是一种典型的线粒体蛋白激酶，调节丙酮酸脱氢酶复合物的活性。 - MCE 生物医学词典 — Master of Bioactive Molecules