Protein phosphatase 1 (PP1) is a widely expressed and highly conserved phosphatase of ~38 kDa that is active only towards phosphoserine/threonine residues and belongs to the phosphoprotein phosphatase (PPP) family of the eukaryotic protein phosphatome [15].

2002年1月15日 · Protein phosphatase 1 (PP1) is a major eukaryotic protein serine/threonine phosphatase that regulates an enormous variety of cellular functions through the interaction of its catalytic subunit (PP1c) with over fifty different established or putative regulatory subunits.

2024年12月19日 · PNUTS-PP1 exhibits antagonistic functions compared with Integrator-PP2A (INTAC) phosphatase, which generally inhibits pause release. Our research thus highlights opposing roles of PP1 and PP2A in modulating genome-wide …

2018年1月1日 · Protein phosphatase 1 (PP1), also known as phosphorylase phosphatase, was first studied in 1943 by Cori and Green in the context of glycogen metabolism, as the enzyme responsible for the conversion of phosphorylase a to phosphorylase b (Cori and Green 1943).

2024年12月25日 · PPP1CA (Protein Phosphatase 1 Catalytic Subunit Alpha) is a Protein Coding gene. Diseases associated with PPP1CA include Venezuelan Equine Encephalitis and Encephalitis. Among its related pathways are GPCR downstream signalling and …

The ubiquitous Ser/Thr Protein Phosphatase 1 (PP1) regulates diverse, essential cellular processes such as cell cycle progression, protein synthesis, muscle contraction, carbohydrate metabolism, transcription and neuronal signaling. However, the ...

2000年1月1日 · PP1 is a major eukaryotic protein serine/threonine phosphatase that regulates diverse cellular processes such as cell-cycle progression, protein synthesis, muscle contraction, carbohydrate metabolism, transcription and neuronal signaling [4].

PP1 is an abundantly expressed, highly conserved Ser/Thr phosphatase, involved in virtually all cell functions including cell cycle, muscle contraction, carbohydrate metabolism, transcription, and neuronal signaling (see Bollen et al., 2010, for a review). Mammalian genomes contain three PP1 catalytic subunit (PP1c) encoding genes, PP1α, -β ...

Protein phosphatase1 (PP1) is a ubiquitous eukaryotic enzyme that regulates a variety of cellular processes through the dephosphorylation of dozens of substrates.

2002年1月15日 · Protein phosphatase 1 (PP1) is a major eukaryotic protein serine/threonine phosphatase that regulates an enormous variety of cellular functions through the interaction of its catalytic subunit (PP1c) with over fifty different established or putative regulatory subunits.