
Functions and therapeutic potential of protein phosphatase 1: …
Protein phosphatase 1 (PP1) is a widely expressed and highly conserved phosphatase of ~38 kDa that is active only towards phosphoserine/threonine residues and belongs to the phosphoprotein phosphatase (PPP) family of the eukaryotic protein phosphatome [15].
Protein phosphatase 1 – targeted in many directions
2002年1月15日 · Protein phosphatase 1 (PP1) is a major eukaryotic protein serine/threonine phosphatase that regulates an enormous variety of cellular functions through the interaction of its catalytic subunit (PP1c) with over fifty different established or putative regulatory subunits.
The phosphatase PP1 sustains global transcription by promoting …
2024年12月19日 · PNUTS-PP1 exhibits antagonistic functions compared with Integrator-PP2A (INTAC) phosphatase, which generally inhibits pause release. Our research thus highlights opposing roles of PP1 and PP2A in modulating genome-wide …
Protein Phosphatase 1 (PP1) - SpringerLink
2018年1月1日 · Protein phosphatase 1 (PP1), also known as phosphorylase phosphatase, was first studied in 1943 by Cori and Green in the context of glycogen metabolism, as the enzyme responsible for the conversion of phosphorylase a to phosphorylase b (Cori and Green 1943).
PPP1CA Gene - GeneCards | PP1A Protein | PP1A Antibody
2024年12月25日 · PPP1CA (Protein Phosphatase 1 Catalytic Subunit Alpha) is a Protein Coding gene. Diseases associated with PPP1CA include Venezuelan Equine Encephalitis and Encephalitis. Among its related pathways are GPCR downstream signalling and …
Structural Basis for Protein Phosphatase 1 Regulation and …
The ubiquitous Ser/Thr Protein Phosphatase 1 (PP1) regulates diverse, essential cellular processes such as cell cycle progression, protein synthesis, muscle contraction, carbohydrate metabolism, transcription and neuronal signaling. However, the ...
Regulation of protein phosphatase-1: Chemistry & Biology - Cell …
2000年1月1日 · PP1 is a major eukaryotic protein serine/threonine phosphatase that regulates diverse cellular processes such as cell-cycle progression, protein synthesis, muscle contraction, carbohydrate metabolism, transcription and neuronal signaling [4].
Protein Phosphatase 1 - an overview | ScienceDirect Topics
PP1 is an abundantly expressed, highly conserved Ser/Thr phosphatase, involved in virtually all cell functions including cell cycle, muscle contraction, carbohydrate metabolism, transcription, and neuronal signaling (see Bollen et al., 2010, for a review). Mammalian genomes contain three PP1 catalytic subunit (PP1c) encoding genes, PP1α, -β ...
Protein phosphatase1 (PP1) - MedChemExpress
Protein phosphatase1 (PP1) is a ubiquitous eukaryotic enzyme that regulates a variety of cellular processes through the dephosphorylation of dozens of substrates.
Protein phosphatase 1--targeted in many directions - PubMed
2002年1月15日 · Protein phosphatase 1 (PP1) is a major eukaryotic protein serine/threonine phosphatase that regulates an enormous variety of cellular functions through the interaction of its catalytic subunit (PP1c) with over fifty different established or putative regulatory subunits.
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