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Trending page - PubMed. Duffy JE, Stachowicz JJ, Reynolds PL, Hovel KA, Jahnke M, Sotka EE, Boström C, Boyer KE, Cusson M, Eklöf J, Engelen AH, Eriksson BK, Fodrie ...

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2017年5月22日 · Many bacterial clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated (Cas) systems employ the dual RNA-guided DNA endonuclease Cas9 to defend against invading phages and conjugative plasmids by introducing site-specific double-stranded breaks in target DNA. Target reco …

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Randomized controlled trials (RCTs) are considered the highest level of evidence to establish causal associations in clinical research. There are many RCT designs and features that can be selected to address a research hypothesis. Designs of RCTs have become increasingly diverse as new methods have …