Distribution of proline‐rich (PxxP) motifs in distinct proteomes ...
2004年2月1日 · We have conducted a survey of proline‐rich (PxxP) motifs in the proteomes of human, mouse, yeast, Mycobacteriumtuberculosis and Plasmodiumfalciparum. Our analyses …
Effect of central PxxP motif in amphipathic alpha-helical peptides …
2023年8月9日 · Therefore, we propose that the central PxxP motif in AHPs provides dynamic conformational behavior in aqueous and membrane-mimetic environments, enhances binding …
Recognition of tandem PxxP motifs as a unique Src homology 3 ... - PNAS
2010年11月22日 · Our complex structure reveals a unique type of SH3 interaction based on recognition of tandem PxxP motifs in the ligand. Strikingly, the specificity pocket of IRTKS SH3 …
The PXXP domain is critical for the protective effect of BAG3 in ...
The purpose of this study is to determine whether the proline-rich (PXXP) domain of BAG3 is necessary for its cellular protection against hypoxia-reoxygenation (H/R) stress by binding to …
Diverse recognition of non-PxxP peptide ligands by the SH3 …
2002年8月8日 · A PxxP motif and a non-PxxP motif in the same polypeptide chain can generate a protein ligand with high affinity and specificity via the multivalent binding mechanism, as seen …
Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a …
2001年1月1日 · Human immunodeficiency virus (HIV) and simian immunodeficiency virus Nef proteins contain a conserved motif with the minimal consensus (PxxP) site for Src homology …
Study of the activation of the PI3K/Akt pathway by the motif of
The present study was conducted to determine whether avian reovirus (ARV) activates the phosphatidylinositol 3-kinase-dependent Akt (PI3K/Akt) pathway according to the PXXP or …
HIV-1 Nef中富含脯氨酸（PxxP）的基序与Src激酶子集的SH3结构 …
人免疫缺陷病毒（HIV）和猿猴免疫缺陷病毒Nef蛋白包含一个保守的基序，具有最小的Src同源区域3（SH3）介导的蛋白-蛋白相互作用的共有（PxxP）位点。
UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance …
2016年8月11日 · Here, we describe a new pathway for maintaining protein homeostasis mediated by the proteasome shuttle factor UBQLN2. The 26S proteasome degrades polyubiquitylated …
Distribution of proline-rich (PxxP) motifs in distinct proteomes ...
2004年3月1日 · We have conducted a survey of proline-rich (PxxP) motifs in the proteomes of human, mouse, yeast, Mycobacterium tuberculosis and Plasmodium falciparum. Our analyses …