Autologous Induced Stem-Cell–Derived Retinal Cells for Macular ...
2017年3月16日 · We assessed the feasibility of transplanting a sheet of retinal pigment epithelial (RPE) cells differentiated from induced pluripotent stem cells (iPSCs) in a patient with …
Human iPS cell derived RPE strips for secure delivery of graft cells …
2021年11月2日 · The use of an RPE sheet allows visual confirmation of placement, but the preparation of a sheet requires considerable time and cost, and involves an invasive surgical …
Tissue engineering RPE sheet derived from hiPSC-RPE cell …
2024年1月16日 · Retinal pigment epithelium (RPE) cell therapy is a promising way to treat many retinal diseases. However, obtaining transplantable RPE cells is time-consuming and less …
Advances in the study of tissue-engineered retinal pigment …
2024年12月1日 · This article reviews the research conducted on RPE cell sheets, explores the progress of RPE sheets in treating RD, and discusses the current status of research on tissue …
Successful Transplantation of Retinal Pigment Epithelial Cells from …
2016年10月11日 · Retinal pigment epithelium (RPE) cells are an especially safe cell type that will seldom form tumors; however, a major problem using autologous iPSCs for standard …
Methods for RPE Sheet Construction Using iPS-CM in Conjunction …
In vitro generation of a functional retinal pigment epithelium (RPE) monolayer sheet is useful and promising for RPE cell therapy. Here, we outline a method to construct engineered RPE …
The Construction of Retinal Pigment Epithelium Sheets with …
2019年7月1日 · Here, we constructed engineered RPE sheets treated by iPS-CM in conjunction with FLI-lenticule scaffolds to help in enhanced RPE characteristics and cilium assembly. Such …
Retinalpigment epithelium (RPE) sheets or RPE suspensions are used for wet-type age-related macular degeneration (AMD) according to the activity levels of exudative changes (A).
Evaluation of Transplanted Autologous Induced Pluripotent Stem …
A comparison of autologous transplantation of retinal pigment epithelium (RPE) monolayer sheet graft with RPE-Bruch's membrane complex graft in neovascular age-related macular …
RPE Cell and Sheet Properties in Normal and Diseased Eyes
2015年1月1日 · In this study, we hypothesized increased variability in the shape and size of RPE cells and increased spatial irregularity by: (1) region-, (2) age-, and (3) disease. To test this …