RAB7 is a small GTPase that has the potential of causing malignancy from over 35 tumor types. It is found that RAB7 is an early induced melanoma driver whose levels can define metastatic …

2024年12月25日 · RAB7A (RAB7A, Member RAS Oncogene Family) is a Protein Coding gene. Diseases associated with RAB7A include Charcot-Marie-Tooth Disease, Axonal, Type 2B and …

2009年5月14日 · Three Rab7 lineages emerged before divergence of monocots and eudicots and subsequent duplications of Rab7 genes occurred in particular angiosperm clades. …

2018年11月8日 · Rab7 (or Ypt7 in yeast) is one of the well-characterized members of the Rab family small GTPases, which serve as master regulators of membrane trafficking in …

Rab7 is a small GTPase that plays a role in the transport and degradation of proteins in endosomes and lysosomes in mammalian cells. Rab7b, is localized to lysosome-associated …

2009年4月27日 · Rab7 is a late endosome-/lysosome-associated small GTPase, perhaps the only lysosomal Rab protein identified to date. Rab7 plays critical roles in the endocytic processes.

Rab7a regulates endocytic transport from early to late endosomes in a process requiring Rab5 to Rab7a conversion. Rab7a also cooperates with other Rab GTPases to facilitate late …

2 天之前 · Rab7 also interacts with the homotypic fusion and protein sorting (HOPS) complex, promoting endosome-lysosome fusion and cargo degradation. This function is crucial for …

Rab7 Antibody detects endogenous levels of total Rab7 protein. Human, Mouse, Rat. Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding …

2025年2月15日 · A deficiency in membrane-associated protein A6 (AnxA6) triggers Rab7 activation, enhancing cholesterol transfer from late endosomes to the ER via a Rab7 and StAR …