Medication-related osteonecrosis of the jaw (MRONJ) is a rare but serious complication that can damage the jawbone. It can occur after treatments like pulling a tooth or treating severe gum disease. It affects some people who are taking or have taken medications to protect bones.

2025年3月5日 · The Ronj at Ross House is an entirely student-run coffeehouse located at 30 Frye Street. Founded in 1997, the Ronj is a space for students to hang out, study, play pool, attend concerts and events, watch movies, and grab a variety of snacks and drinks.

In most cases of MRONJ, local therapies can be successful. The fact that more complex treatment is required for a few patients should not impact decision-

Medication-related osteonecrosis of the jaw (MRONJ) is a major problem that can occur in people taking certain medications such bisphosphonates and denosumab. It can be used to treat osteoporosis or cancer.

2023年9月25日 · 药物相关性颌骨坏死（medication-related osteonecrosis of the jaw，MRONJ）是指因恶性肿瘤骨转移、骨质疏松等疾病使用双膦酸盐类药物（bisphosphonates, BPs）、抗血管生成类药物或类固醇类药物等所致的颌骨代谢紊乱及骨坏死类疾病。 在口服药物治疗骨质疏松症的患者中，MRONJ的发病率约为0.02%～0.04%；而通过静脉注射治疗肿瘤骨转移的癌症患者中，MRONJ的发病率显著升高，可达0.7%～9% [1]。 该病临床表现为局部红肿、疼 …

Medication-related osteonecrosis of the jaw (MRONJ) is a severe adverse drug reaction, consisting of progressive bone destruction in the maxillofacial region of patients.

MRONJ is characterized by nonhealing exposed bone in patients with a history or ongoing use of bisphosphonates (particularly administered via high-dose IV) and other antiresorptive agents (eg, denosumab), or an antiangiogenic agent and no history …

Medication-related osteonecrosis of the jaw (MRONJ) is a rare, severe debilitating condition from unknown causes. It is characterized by nonhealing exposed bone in a patient with a history of antiresorptive or antiangiogenic agents in the absence of …

List of Drugs Associated with MRONJ - March 2024 (PDF) – a list of the drugs with an MHRA Drug Safety Update for MRONJ. There is an increased risk of oral health complications for patients prescribed anti-resorptive or anti-angiogenic drugs (medication-related osteonecrosis of the jaw, MRONJ).

目的：探讨经济有效的治疗放射性颌骨坏死（RONJ）的手术方式。 方法77例RONJ根据颌骨坏死的范围、软组织条件选择不同治疗方式。 方案1：骨坏死范围局限，牙龈及周围软组织无明显炎症的采用局部刮治或方块切除术；方案2：骨坏死范围较大、周围软组织炎症明显和（或）伴有明显纤维化的病例在控制炎症后，扩大切除同时行血管化游离复合组织瓣修复。