2022年1月21日 · SCP4是一种磷酸酶，即能从蛋白质中清除磷酸基团来调节细胞活性的蛋白质，另外一种名为激酶的蛋白质则能将这些磷酸基团放回去；从蛋白质上增加 ...

2025年3月3日 · Foundation Universe Hub - For information on Sites, Mobile Task Forces, Departments, and more. Audio Adaptations - Links to audio read-outs of various articles on the …

We found that SCP4 enhanced the transcription of FoxO1/3a target genes encoding PEPCK1 and G6PC, key enzymes in hepatic gluconeogenesis. Ectopic expression of SCP4 increased, while …

2022年1月11日 · We provide evidence that SCP4 regulates STK35/PDIK1L through two distinct mechanisms: catalytic removal of inhibitory phosphorylation and by promoting kinase stability. …

2017年12月12日 · Identification of SCP4 as a key regulator of FoxOs in hepatic gluconeogenesis advances our understanding of glucose homeostasis. The study by Cao et al. (13) elegantly …

SCP4 represents a novel nucleus-resident phosphatase identified in our previous study. The primary aim of this study was to elucidate the function of SCP4 in the progress of cartilage …

SCP4, also known as carboxy‐terminal domain (CTD) small phosphatase like 2 (CTDSPL2), act as a metal‐dependent serine/threonine phosphatase capable of directly dephosphorylating …

2023年9月8日 · Level 1 clearance is required for basic access to SCP-004-1; Level 4 clearance is required for use of SCP-004-2 to -13. Description: SCP-004 consists of an old wooden barn …

Knockdown of SCP4 significantly suppressed FoxO1/3a-mediated expression of Atrogin-1 and MuRF-1 and prevented muscle wasting in mice with CKD. Thus, SCP4 is a novel regulator of …

The small C-terminal domain phosphatase 4 (SCP4), also known as carboxy-terminal domain (CTD) small phosphatase like 2 (CTDSPL2), is a novel phosphatase in the nucleus identified …