
TP63 - Wikipedia
Tumor protein p63, typically referred to as p63, also known as transformation-related protein 63, is a protein that in humans is encoded by the TP63 (also known as the p63) gene. [5][6][7][8]
TP63 Gene - GeneCards | P63 Protein | P63 Antibody
2024年12月25日 · TP63 (Tumor Protein P63) is a Protein Coding gene. Diseases associated with TP63 include Adult Syndrome and Limb-Mammary Syndrome. Among its related pathways are …
P63 - 维基百科,自由的百科全书
p63,亦作TP63,全稱腫瘤蛋白p63(tumor protein p63)或惡性轉化相關蛋白63(transformation-related protein 63),在人體內由TP63基因編碼 [6] [7] [8] [9] 。p63的發現是在p53基因發現 …
TP63 gene - MedlinePlus
The TP63 gene provides instructions for making a protein called tumor protein p63 (also known simply as p63). The p63 protein functions as a transcription factor, which means it attaches …
TP63-Related Disorders - GeneReviews® - NCBI Bookshelf
2010年6月8日 · Heterozygous TP63 variants have been associated with five different syndromes with overlapping phenotypic features: ectrodactyly, ectodermal dysplasia, cleft lip/palate …
研究揭示肿瘤蛋白P63在鳞癌免疫逃逸中的关键作用----中国科学院
2024年5月21日 · 研究发现,在小鼠体内模型中,下调TP63表达,增强了PD-1抗体的抗肿瘤免疫疗效。相关研究成果发表在《自然-通讯》(Nature Communications)上。 鳞癌是常见的侵袭 …
TAp63 and DeltaNp63 in cancer and epidermal development
2007年2月1日 · TAp63 shows clear pro-apoptotic activity, mediated both by death receptors (CD95, TNF, TRAIL) and mitochondrial (bax, puma) pathways. Conversely, DeltaNp63 …
TP63 tumor protein p63 [Homo sapiens (human)] - Gene - NCBI
2025年2月8日 · Title: TP63 truncating mutation causes increased cell apoptosis and premature ovarian insufficiency by enhanced transcriptional activation of CLCA2. Reciprocal inhibition …
肿瘤蛋白 p63(TP63)基因 | MCE - MCE-生物活性分子大师
该基因编码 p53 转录因子家族的成员。 p53 家族蛋白的功能域包括一个 N 端反式激活域、一个中心 DNA 结合域和一个寡聚化域。 该基因的选择性剪接和替代启动子的使用导致编码不同亚型 …
团队合作揭示了TDP-43/TP63在食管鳞状细胞癌中的作用机理
2024年7月19日 · 肿瘤蛋白63(tp63)是escc中的一种主转录因子(tf),它与其他tf协同调节靶癌基因的增强子和/或启动子,从而促进肿瘤的发生。 TAR-DNA结合蛋白-43(TDP-43)是一种 …