
血栓素B2 - 百度百科
血栓素 (thromboxane,TXB2 [2])是前列腺素中的一种,由血小板产生,具有血小板凝聚及血管收缩作用,与前列腺素作用相反,两者动态平衡以维持血管收缩功能及血小板聚集作用。 TXA2生物半衰期仅30s,迅速转化为无活性的血栓素B2 (TXB2)。 血浆:男性: (132±55)ng/L;女性: (116±30)ng/L。 血栓素水平变化见于:动脉粥样硬化、心绞痛、冠心病、糖尿病、高脂血症等增高,TXA2/PGI2比值升高易于导致血小板聚集、血栓形成,促使动脉粥样硬化和冠心病。 出血 …
Thromboxane B2 - Wikipedia
Thromboxane B2 (TXB2) is an inactive metabolite/product of thromboxane A2. It is almost completely cleared in the urine. It itself is not involved in platelet activation and aggregation in case of a wound, but its precursor, thromboxane A2, is.
Thromboxane B2 (血栓素 B2) - 仅供科研 | Prostaglandin …
Thromboxane B2 是一种前列腺素衍生物,在过敏反应时释放。 Thromboxane B2 诱导动脉收缩和血小板聚集。 * Please select Quantity before adding items. Thromboxane B2 is a prostaglandin derivative that is released during anaphylaxis. Thromboxane B2 induces arterial contraction and platelet aggregation. Room temperature in continental US; may vary elsewhere.
脑梗死患者的血浆TXB2和6酮PGF1α变化及其与血脂的关系 - 道客 …
结果 与健康人相比,发现脑梗死患者的血浆TX B2升高、6 -酮-PG F1!降低、TX B2/6 -酮-PG F1!升高。 LD L -C及A PO -B与TX B2、TX B2/6 -酮-PG F1!呈正相关, 与6 -酮-PG F1!呈负相关。 而H D L -C与6 -酮-PG F1!呈正相关。 TG与TX B2/6 -酮-PG F1!呈正相关。 结论 脑梗死患者的TX B2和6 -酮-PG F1!变化与脂质代谢紊乱可能有一定关系。
Thromboxane B2 | C20H34O6 | CID 5283137 - PubChem
Thromboxane B2 is an eicosanoid and biologically inactive metabolite of thromboxane A2. Thromboxane B2 is released during anaphylaxis. As thromboxane A2 has a short half-life, the levels of thromboxane B2 can be used to indirectly measure the …
Thromboxane B2 - an overview | ScienceDirect Topics
TXA2 will also be converted into thromboxane B2 (TXB2) which is its stable metabolite [73]. The activation of platelets via collagen or vWF induces the activation of the arachidonic acid pathway, causing platelets to secrete TXA2, that will be taken up by the TXA2 receptor on platelets further inducing platelet activation [ 74 ].
血栓素又称凝血噁烷、凝血烷,能引起动脉收缩,诱发血小板聚 …
2022年5月9日 · 血栓素水平变化见于:动脉粥样硬化、心绞痛、冠心病、糖尿病、高脂血症等增高,TXA2/PGI2比值升高易于导致血小板聚集、血栓形成,促使动脉粥样硬化和冠心病。 出血、损伤和 内毒素休克 动物血浆中TXB2显著增加,这与休克时肺循环阻力升高有关。 慢性肾衰患者尿中TXB2和6-酮-PGF1α下降。 肾血管性高血压、肾病综合征和BATTER综合征患者尿中PG亦有显著性变化。 恶性肿瘤患者动脉组织中TXA2有所改变,PGI2、TXA2正常时,能阻止肿瘤细胞侵 …
Relationship of blood thromboxane-B2 (TxB2) with lipid ... - PubMed
The elevated blood level of TxB2 (hyperaggregability of platelets) is significantly related to the level of lipid peroxidation products (oxidative stress) in type 1 diabetic patients. Supplementation of modest doses of vitamin E (100 IU/day) significantly lowers blood TxB2 and …
Aspirin response: Differences in serum thromboxane B2 levels …
Serum thromboxane B2 (TxB2) is a specific marker of platelet inhibition by aspirin. Yet, TxB2 levels differ by up to 10-fold between some aspirin-treated patient cohorts. This study aimed to identify factors responsible for differences in serum TxB2 between cohorts in the ADRIE study (n = …
Thromboxane B2, 6-keto-PGF1α, PGE2, PGF2α, and PGA1
1984年1月1日 · The plasma profiles of thromboxane B2 (TXB2), 6-keto-PGF,,, PGE2, PGF2a, and PGA, were investigated by means of a sensitive radioimmunoassay technique in 40 patients with arteriosclerosis obliterans and in 30 healthy control subjects.