Temozolomide was restarted 2 months later; the patient again developed a fever. This time the fever was accompanied by a diffuse erythematous skin rash that progressed to an extensive, full-body, desquamative skin rash. The rash was treated with moisturizing cream along with intravenous and topical corticosteroids and antibiotics.

Within 10 days of resuming TMZ, the patient noted an itchy rash with persistent individual lesions that did not come and go. On cutaneous examination, discrete red plaques and nodules were found on the bilateral upper extremities, thighs, and back .

2024年9月4日 · A case of diffuse erythematous skin rash that progressed to an extensive full body desquamative skin rash has been reported. Even though temozolomide was permanently discontinued, the patient continued to experience the rash on a …

2015年7月29日 · Keywords: ADR, adverse drug reaction; TMZ, temozolomide; adverse drug reaction; dermal hypersensitivity reaction; panniculitis; rash; temozolomide.

Dermatol Ther. 2021 Mar;34 (2):e14771. doi: 10.1111/dth.14771. Epub 2021 Jan 21. 1 Department of Dermatology, Wayne State University, Detroit, Michigan, USA. 2 Wayne State University School of Medicine, Detroit, Michigan, USA.

2024年12月3日 · Temozolomide may cause allergic reactions, which can be serious. Stop using temozolomide and get help right away if you have any of the following symptoms of a serious allergic reaction.

2023年1月28日 · Drug rash with eosinophilia and systemic symptoms syndrome (DRESS syndrome) is a rare and potentially life-threatening hypersensitivity reaction that presents with cutaneous rash, lymphadenopathy, eosinophilia and internal organ involvement. 1 Temozolomide is an alkylating agent most often used for the management of high-grade gliomas.

Contact your health care provider right away if you notice fevers or flu-like symptoms with a rash. The rash may be red or purple and then turn into blisters or peeling of the skin. Or, you might notice a red rash with swelling of the face, lips or lymph nodes in your neck or under your arms.

2023年9月20日 · Temodar (temozolomide) is an alkylating agent that may be used to treat certain types of brain tumors in adults, specifically glioblastoma multiforme and anaplastic astrocytoma. It is used for: Newly diagnosed glioblastoma together with radiotherapy and then as …

2012年1月6日 · Temozolomide was restarted 2 months later; the patient again developed a fever. This time the fever was accompanied by a diffuse erythematous skin rash that progressed to an extensive, full-body, desquamative skin rash. The rash was treated with moisturizing cream along with intravenous and topical corticosteroids and antibiotics.