UBTF Gene - GeneCards | UBF1 Protein | UBF1 Antibody
2024年12月25日 · UBTF (Upstream Binding Transcription Factor) is a Protein Coding gene. Diseases associated with UBTF include Neurodegeneration, Childhood-Onset, With Brain …
上游结合因子1 - 百度百科
上游结合因子1（Upstream binding factor 1，缩写UBF1）是一种由人类基因UBTF所编码的蛋白质。UBTF是18S、5.8S和28S的核糖体RNA的转录所必须的转录因子，和SL1因子（一个四聚 …
UBTF - Wikipedia
UBTF is a transcription factor required for expression of the 18S, 5.8S, and 28S ribosomal RNAs, along with SL1 (a complex of TBP (MIM 600075) and three TBP-associated factors or 'TAFs') …
UBTF - 维基百科，自由的百科全书
核仁转录因子1 （Nucleolar transcription factor 1）又叫 上游结合转录因子 （Upstream binding transcription factor，缩写 UBTF）或 上游结合因子1 （Upstream binding factor 1，缩写 …
Regulation of Upstream Binding Factor 1 Activity by Insulin-like …
The upstream binding factor 1 (UBF1) is one of the proteins in a complex that regulates the activity of RNA polymerase I, which controls the rate of ribosomal RNA (rRNA) synthesis. We …
Protein kinase Cι promotes UBF1-ECT2 binding on ribosomal DNA ... - PubMed
2020年6月12日 · Recently, we demonstrated that a significant pool of ECT2 localizes to the nucleolus of non-small-cell lung cancer (NSCLC) cells, where it binds the transcription factor …
Functional Cooperativity Between Transcription Factors UBF1 …
The human ribosomal RNA promoter contains two distinct control elements (UCE and core) both of which are recognized by the sequence-specific DNA binding protein UBF1, which has now …
UBF levels determine the number of active ribosomal RNA genes …
2008年12月12日 · Thus, UBF1 levels regulate active rRNA gene chromatin during growth and differentiation. Ribosome biogenesis plays an essential role in growth control, and transcription …
Protein kinase Cι promotes UBF1–ECT2 binding on ribosomal …
2020年6月6日 · Biochemical and MS-based analyses revealed that protein kinase Cι (PKCι) directly phosphorylates UBF1 at Ser-412, thereby generating a phosphopeptide-binding …
Genome wide mapping of UBF binding-sites in mouse and human ... - PubMed
2015年1月5日 · Our data demonstrate that UBF1/2 bind highly active Pol II-transcribed genes and mediate their expression without recruiting Pol I. Furthermore, we reported ChIP-sequencing …