The Career Conversion Programme for Registered Nurses (Degree) [CCP-RN (Degree)] is an intensive 2-year programme with combination of theoretical and 1,280 hours on clinical practicum in community and hospital/healthcare settings.

抗环瓜氨酸多肽抗体(anti-cyclic peptide containing citrulline，anti-CCP)：是环状聚胍蛋白的多肽片段，以IgG型为主的抗体。 抗CCP抗体是由RA患者B淋巴细胞自发分泌的，而其他疾病患者和正常人群B淋巴细胞并不自发分泌抗CCP抗体。

2023年11月17日 · The hallmark of RA is the presence of rheumatoid factor (RF) and anti-cyclic citrullinated peptide (CCP) antibodies. Based on the presence of anti-CCP antibodies, RA can be classified into two subsets: anti-CCP positive and anti-CCP negative RA, having distinct genetic and environmental risk factors and different pathogenesis.

The overall evidence obtained by the present suggests that anti-CCP antibody is a significant serologic marker for RA in the Turkish population. With acceptable specificity (87%) and moderate sensitivity (69%), anti-CCP antibody tests play an important role in confirming the diagnosis of RA in a Turkish population. References. 1.

2013年1月22日 · Anti-CCP positivity, at both low and high titer, and arthritis of hand joints significantly predicted RA at two years, risk increasing in subjects with high anti-CCP titers at baseline. Moreover, time to RA diagnosis was shorter in patients with high anti-CCP2 titers at enrollment with respect to those with low antibody concentration.

2022年9月5日 · apf抗原成分是存在人颊黏膜上皮细胞胞质内的不溶性蛋白质，与ra呈良好的线性关系，其对ra的诊断特异性随抗体滴度升高而增加，但与rf之间无明显相关，而与抗ccp抗体密切相关。

This study compares the diagnostic performance of a second generation anti-cyclic citrullinated peptide antibody (CCP2) with a third generation anti-CCP antibodies assay (CCP3), as well as the combination of both tests. Serum samples of 127 patients were analyzed.

2005年9月16日 · Although a positive anti-CCP test does not appear to identify patients with distinct clinical characteristics at presentation, it is superior to RF regarding diagnostic specificity for RA, and the anti-CCP test predicts more severe disease course and outcome.

CCP（cyclic citrullinated peptide，环 瓜氨酸 肽）指的是瓜氨酸是 类风湿病 患者血清中抗 丝聚蛋白 相关抗体识别的主要组成性 抗原决定簇 成分。 采用CCP为抗原基质检测 类风湿 患者血清中的抗CCP抗体， 具有较高的 敏感性 和极高的 特异性。 有研究提示抗CCP参与了类风湿发病过程。 除此之外，抗CCP抗体阳性的类患者更容易出现关节的骨质损坏。 因此，抗CCP抗体阳性者的愈后可能较差，应采取更积极的 治疗措施。 CCP（cyclic citrullinated peptide，环瓜氨酸肽）指 …

Anti-CCP assays (antibody to cyclic citrullinated peptides) possess a high specificity for RA (rheumatoid arthritis). In lack of an international reference material the absolute values among different assays strongly diversify. The cut-off showed a variance from 5 U/mL Euroimmun anti-CCP to 25 U/mL …