2018年12月12日 · The main difference between lipoprotein lipase and hormone sensitive lipase is that the lipoprotein lipase (LPL) is attached to the luminal surface of the endothelial cells in the capillaries of the adipose tissue whereas the hormone …

Lipoprotein lipase (LPL) (EC 3.1.1.34, systematic name triacylglycerol acylhydrolase (lipoprotein-dependent)) is a member of the lipase gene family, which includes pancreatic lipase, hepatic lipase, and endothelial lipase.

2019年4月3日 · Lipoprotein lipase (LPL) is a rate-limiting enzyme for the hydrolysis of triglycerides (TG). Hundreds of genetic variants including single nucleotide polymorphisms have been identified across the 30Kb gene locus on chromosome 8q22.

2018年4月3日 · Lipoprotein lipase (LPL) mediates hydrolysis of triglycerides (TGs) to supply free fatty acids (FFAs) to tissues. Here, we show that LPL activity is also required for...

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2020年11月6日 · Lipoprotein lipase (LPL) is a key enzyme in lipid and lipoprotein metabolism. The canonical role of LPL involves the hydrolysis of triglyceride-rich lipoproteins for the provision of FFAs to metabolic tissues. However, LPL may also contribute to lipoprotein uptake by acting as a molecular bridge bet …

LPL is the rate-limiting step in lipolysis of chylomicrons and VLDL. LPL is produced in myocytes, adipocytes, and several other cell types and stored in the Golgi apparatus for either intracellular degradation or release to the cell surface.

脂蛋白脂酶(lipoprotein lipase,LPL)是甘油三酯降解为甘油和游离脂肪酸(FFA)反应的限速酶,与机体的脂质代谢及肥胖与否密切相关.白色脂肪组织(WAT)中的LPL活性升高有助于机体脂质的贮存,棕色脂肪组织(BAT)的LPL活性与机体产热有关,而骨骼肌的LPL活性升高有利于机体利用 ...

2022年11月23日 · 淋巴浆细胞性淋巴瘤 (lymphoplasmacytic lymphoma, LPL，旧称淋巴浆细胞样淋巴瘤)是一种罕见的成熟B细胞淋巴瘤，常侵犯骨髓，少数情况下也可侵犯脾脏和/或淋巴结。华氏巨球蛋白血症(Waldenström macroglobulinemia, WM)是一种具有临床病理性特征的疾病，与血液中IgM型单克隆 ...

We assessed the roles of LpL (lipoprotein lipase)-mediated lipid uptake in macrophage polarization in vitro and in several important tissues in vivo. Approach and Results: We created mice with both global and myeloid-cell specific LpL deficiency.