2024年12月24日 · CBY1 (Chibby 1, Beta Catenin Antagonist) is a Protein Coding gene. Diseases associated with CBY1 include Joubert Syndrome 1 and Prostate Cancer. Among its related pathways are Signaling by WNT and Deactivation of the beta-catenin transactivating complex.

β-连环蛋白是一种转录激活剂和癌蛋白，参与多种癌症的发展。 由该基因编码的蛋白质直接与 β-连环蛋白的 C 末端区域相互作用，通过与转录因子竞争结合 β-连环蛋白来抑制致癌的 β-连环蛋白介导的转录激活。 已发现该基因的两个转录本变体编码不同的亚型。 [RefSeq 提供，2008 年 7 月] Beta-catenin is a transcriptional activator and oncoprotein …

2025年2月8日 · 14-3-3epsilon and 14-3-3zeta are identified as Cby-binding partners. intrinsically disordered TC-1 interacts with Cby via its transient helical structure; CBY promotes adipocyte differentiation through inhibition of beta catenin signaling.

Protein chibby homolog 1 is a protein that in humans is encoded by the CBY1 gene. [5][6][7] Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers.

2024年6月17日 · Title: DNA methyltransferase 1 drives transcriptional down-modulation of β catenin antagonist Chibby1 associated with the BCR-ABL1 gene of chronic myeloid leukemia. Study showed that expression of Cby protein was strongly downregulated in laryngeal squamous cell carcinoma (LSCC) tumor tissues in comparison to normal laryngeal mucosa samples.

2017年10月10日 · Chibby 1 (CBY1) is a small and evolutionarily conserved protein, which act as β-catenin antagonist. CBY1 is encoded by C22orf2 (22q13.1) Its antagonistic function on β-catenin involves the direct interaction with:

Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.

Carbify USD Price Today - discover how much 1 CBY is worth in USD with converter, price chart, market cap, trade volume, historical data and more.

2022年5月20日 · 保守的 15 kD 卷曲螺旋 CBY1 蛋白主要定位于母中心粒/基体。 CBY1 作为远端附属物/过渡纤维蛋白的环状特征定位于成熟纤毛的基部，并且在纤毛的形成和功能中具有关键作用（Li 等人总结，2016）。 武丸等人（2003） 使用 β-连环蛋白的 C 末端作为诱饵，在酵母 2-杂交筛选中鉴定了 Chibby（CBY）。 从果蝇到人类，CBY 在进化上是保守的； 人 CBY 含有 126 个氨基酸，具有预测的核定位信号和卷曲螺旋结构域。 Northern 印迹分析检测到一种 1.2 kb …

Immunohistochemical analysis of paraffin-embedded human heart using 12239-1-AP (CBY1 antibody) at dilution of 1:50 (under 40x lens). Cited in 5 publications. CBY1 antibody for WB, IP, IHC, ELISA and reacts with human, mouse, rat.