
One-on-One Coaching with ICMA CoachConnect | icma.org
Ideal for students, early to mid-career, and seasoned professional managers, this program offers personalized online mentoring sessions with experienced local government professionals. Access is unlimited for ICMA and Coaching Partner members. Non-members receive 12 …
ICAM-1 - 百度百科
ICAM-1(intercellular cell adhesion molecule-1 即细胞间黏附分子-1),又叫作CD54,属于黏附分子中免疫球蛋白超家族(IGSF)中的成员,是介导黏附反应重要的一个黏附分子。 ICAM-1 在静息的血管内皮细胞(VEC)上呈低水平表达,通过与血管内皮细胞表面上的特异性受体结合而发挥其生物学活性。 作为白血球和内皮细胞跨膜的蛋白质,ICAM1在稳定细胞间相互作用和促进白血球和内皮细胞的迁移起到重要作用。 ICAM-1 的受体有LFA-1 (lymphocyte function associated …
什么是细胞间粘附分子1 (ICAM-1)? - 知乎
细胞间粘附分子1 (icam-1) 也称为cd54,是一个几乎无所不在的跨膜糖蛋白,通常表达于内皮细胞和免疫细胞,对白细胞迁移和活化具有关键作用。 它与CD11a/CD18或CD11b/CD18型整合素结合,也会被鼻病毒作为受体利用。
Institute of Certified Management Accountants (ICMA)
Prometric’s new CMA Exam Simulation provides an intuitive, easily accessible mock exam experience, offering an interactive simulation of the testing interface and specific exam functionality you will find at the testing center on exam day. The CMA Exam Simulation is free to CMA candidates and includes:
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【靶点科普】ICAM-1:从免疫监视到病理过程 - 知乎
ICAM-1(Intercellular Cell Adhesion Molecule-1),又叫CD54,中文名为细胞间黏附分子-1,主要功能是介导细胞间的黏附反应。 粘附分子是细胞功能、组织完整性和稳态的关键调节因子,不仅介导细胞间的相互作用,而且通过与细胞骨架和各种衔接蛋白的结合,触发细胞内信号传导,以响应特定和局部的提示,如炎症刺激后上皮细胞和免疫细胞中的ICAM-1表达增加。 ICAM-1是许多细胞功能的主要调节因子。 ICAM-1启动子包含多种转录因子的结合位点,如AP-1、SP、NF-κB …
2025 ICMA Assistant Chief Administrative Officer Exchange
6 天之前 · Are you an ICMA member eager to explore the inner workings of a different local government? The Assistant Chief Administrative Officer (ACAO) Exchange is the perfect opportunity for you. This dynamic preconference event, scheduled for Friday, October 24, 2025, is specifically designed for deputies, assistants, and assistant to's seeking inspiration and insights.
ICMA Resource Center
2025年2月24日 · Welcome to the ICMA Resource Center! Our collection offers a wealth of valuable resources tailored for local government professionals. Here, you’ll find timely and actionable research and content from ICMA, along with carefully curated third-party materials designed to support your work in the public sector.
ICAM-1:炎症,损伤缓解和肿瘤发生过程中细胞 ... - X-MOL
2020年3月17日 · icam-1是一种细胞表面糖蛋白,是一种粘附受体,以调节白细胞从循环到炎症部位的募集而闻名。 但是,除了血管内皮细胞,响应炎症刺激,还可以在上皮和免疫细胞上强烈诱导ICAM-1的表达。
肿瘤标志物(12)|李策教授谈外泌体ICAM-1促进免疫抑制的分子机 …
2022年5月13日 · 本研究表明,肿瘤外泌体表面的ICAM-1介导了肿瘤外泌体与CD8 T细胞的黏附,且该黏附作用是肿瘤外泌体PD-L1介导免疫抑制效应的前提条件,提示肿瘤外泌体作为完整功能单元,其表面分子存在着协同作用。 研究背景. LFA-1:淋巴细胞功能相关抗原1,又称αLβ2或 CD11a/CD18,是表达于T细胞表面的关键整合素,其主要配体是ICAM-1,在免疫突触形成过程中,T细胞与APC细胞相互作用,在突触中央发生LFA-1和ICAM-1的结合,这一过程优先于TCR …