Antibody-Mediated Clearance of Amyloid-β Peptide from Cerebral …
Serial imaging of individual segments of CAA-laden leptomeningeal vessels was performed at day 0 (A1, B1), day 7 (A2, B2), and day 14 (A3, B3) relative to initiation of continuous delivery of …
Exacerbation of Cerebral Amyloid Angiopathy-Associated …
2005年1月19日 · We characterized the binding properties of several monoclonal anti-Aβ antibodies to deposited Aβ in brain parenchyma and CAA. Biochemical analyses …
APOE Genotype Differentially Modulates Effects of Anti-Aβ, …
2017年1月31日 · Here we investigated how APOE genotype influences response to anti-Aβ immunotherapy. APPSW/PS1dE9 (APP) transgenic mice with targeted replacement of the …
Exacerbation of cerebral amyloid angiopathy-associated ... - PubMed
2005年1月19日 · We characterized the binding properties of several monoclonal anti-Abeta antibodies to deposited Abeta in brain parenchyma and CAA. Biochemical analyses …
Four-dimensional microglia response to anti-Aβ treatment in APP ...
Effect of anti-Aβ antibody (10D5) treatment on microglia burden, number of microglial cells, microglia size and number of processes from cell bodies in APP swe/PS 1dE9xCX3CR1–GFP …
Binding of anti-Aβ antibody (10D5, Eli Lilly, (A)), 5 (B), and ...
Binding of anti-Aβ antibody (10D5, Eli Lilly, (A)), 5 (B), and thioflavin S (C) to Aβ plaques in AD brain near/adjacent tissue sections. Amyloid in postmortem frontal lobe of a 90-year-old male....
Cerebrovascular lesions induce transient β-amyloid deposition
2011年11月25日 · To test whether the increased plaque deposition was restricted to dense-core versus diffuse amyloid aggregates, we used 10D5, an N-terminal specific anti-β-amyloid …
Variable Details | RADC
We created a semiquantitative summary of cerebral amyloid angiopathy (CAA) pathology in 4 neocortical regions: midfrontal, midtemporal, parietal, and calcarine cortices.
CAA analysis. APOE genotype differentially modulates the CAA …
Representative microphotographs of Th-S stained coronal brain sections through the somatosensory cortex from untreated age-matched (Age control) mice, and mice receiving …
Aβ (10D5) | ALZFORUM
Clonality: monoclonal Host: Mouse Isotype: IgG 1 Source: amyloidβ 10D5 (F Bard, Elan Pharmaceuticals, South San Francisco, CA paper: Bard, et al., PNAS Feb 3, 2003) Reference: …