Brequinar reduces virus progeny production by >90%, with EC 50 of 17 nM. Brequinar (5?μM) also inhibits other orthopoxviruses, and blocks virus DNA replication. Brequinar does not affect …

介绍一种新型免疫抑制剂一bqr的分子结构、药代动力学特性及其对淋巴细胞选择性抑制作用机制。 强调了其对异种移植排斥反应和加速型排斥反应的显著疗效。

2023年11月1日 · Ferroptosis shows potential for increasing the responsivity of CBI by inducing immunogenic cell death (ICD) process. Herein, we developed a mitochondrial-targeted …

Herein, we developed a mitochondrial-targeted liposome loaded with brequinar (BQR) (BQR@MLipo) for enhancing the mitochondrial-related ferroptosis in bladder cancer in situ.

The bootstrapped quantile regression (BQR) could be an appropriate statistical approach to mitigate these problems because this robust method combines the methodological advantages …

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