Identification of key genes and pathways associated with …
In summary, differentially expressed genes and key modules contributing to initiation and progression in ESCC were identified by means of WGCNA. Pathways including cellular …
Characterization of genetic rearrangements in esophageal …
2012年8月24日 · In this study, we describe CNAs and unbalanced genetic rearrangements in six ESCC cell lines through a combination of M-FISH and 44K array-CGH techniques. We found …
Targeting 17q23 amplicon to overcome the resistance to anti …
2018年11月9日 · Chromosome 17q23 amplification occurs in ~11% of human breast cancers. Enriched in HER2+ breast cancers, the 17q23 amplification is significantly correlated with poor …
Stabilization of miRNAs in esophageal cancer contributes to ...
2019年1月1日 · In this review, we discuss key miRNAs and their contributions in sensitivity and resistance to radiotherapy in esophageal cancer. We also focus on their potential utility as …
EIF3H promotes aggressiveness of esophageal squamous cell …
We found that EIF3H is significantly upregulated in esophageal cancer and ectopic expression of EIF3H in ESCC cell lines promotes cell proliferation, colony formation, migration and invasion. …
The integrated molecular and histological analysis defines ... - Nature
2024年10月18日 · Here we show that ESCC can be categorized into differentiated, metabolic, immunogenic and stemness subtypes based on bulk and single-cell RNA-seq, each exhibiting …
项目文章丨Cancer Cell：单细胞时空多组学揭示上皮细胞激活成纤 …
本研究结果为理解 ESCC 癌变的进展提供了思路，并有利于早期癌症的发现和临床治疗。 该研究中基于 10x Genomics 平台的单细胞测序及 Visium 空间转录组测序由博奥晶典提供技术服务 …
Functional Polymorphisms in Interleukin-23 Receptor and …
Our results obtained by analyzing 684 ESCC patients and 1064 healthy controls showed that the functional variation rs10889677 C in the IL-23R was associated with decreased risk for …
失巢凋亡效应分子bcl-2转录抑制因子1的研究进展 - 肿瘤研究与临床
Bit1在食管鳞状细胞癌（ESCC）组织中表达水平显著升高，且与淋巴结转移、TNM分期密切相关 。TAp63γ是p53家族新成员p63 TA型同源体，具有促凋亡功能。 TAp63γ是p53家族新成 …
A platform of functional studies of ESCC-associated gene …
2024年11月26日 · Here, we report a convenient platform with CRISPR-Cas9-mediated introduction of genetic alterations and orthotopic transplantation to generate a series of …