2009年4月8日 · Here, we demonstrate that the probe mobility of two different spin-labeled nucleotide analogs in the kinesin-1 nucleotide pocket is restricted upon binding of the tail domain to kinesin-1 heads. This conformational restriction is distinct from the microtubule-induced changes in the nucleotide pocket.

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Wilson C, Naber N, Cooke R. PMID: 33364594; PMCID: PMC7753139. Piperine, an alkaloid inhibiting the super-relaxed state of myosin, binds to the myosin regulatory light chain. Arch Biochem Biophys. 2018 12 01; 659:75-84. Tolkatchev D, Elnatan D, Nogara L, Ly T, Naber N, Haak K, Meech R, Cooke R, Kostyukova AS. PMID: 30287237; PMCID: PMC6699511.

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2009年4月1日 · Europe PMC is an archive of life sciences journal literature.

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19348763. Authors: Yao Liang Wong, Kristen A. Dietrich, Nariman Naber, Roger Cooke, Sarah E. Rice Abstract: We have used electron paramagnetic resonance and fluorescence spectroscopy to study the interaction between the kinesin-1 head and its regulatory tail domain. The interaction between the tails and the enzymatically active heads has been ...

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