2000年11月29日 · We determined structures from several crystal forms of the RevErb-DNA complex and analyzed the patterns of protein-DNA interactions and DNA distortions. We found a significant and consistent DNA distortion at a TA step directly preceding the first consensus 5'-AGGTCA-3' recognition sequence.

2023年7月21日 · 氢原子转移（hat）过程能够实现c–h键的区域选择性功能化，是选择性构建 c(sp 3) ‒ c(sp 3) 键最有效的方法之一。特别是，以杂原子为中心的自由基（如o•、n•），通常经历分子内1,5-hat反应产生异位的碳中心自由基（c•），此类反应在现代有机合成中得到了 ...

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1GA5: CRYSTAL STRUCTURE OF THE ORPHAN NUCLEAR RECEPTOR REV-ERB(ALPHA) DNA-BINDING DOMAIN BOUND TO ITS COGNATE RESPONSE ELEMENT. PDB ID: 1GA5 Download: MMDB ID: 72125: PDB Deposition Date: 2000/11/29: Updated in MMDB: 2017/10: Experimental Method: x-ray diffraction. Resolution:

Authors: M.L.Sierk,Q.Zhao,F.Rastinejad Key ref: M.L.Sierk et al. (2001). DNA deformability as a recognition feature in the reverb response element.

1ga5: crystal structure of the orphan nuclear receptor rev-erb(alpha) dna-binding domain bound to its cognate response element

1ga5 is a 8 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. NR1D1_HUMAN Functions as a constitutive transcriptional repressor. In collaboration with SP1, activates GJA1 transcription (By similarity).

1ga5: crystal structure of the orphan nuclear receptor rev-erb(alpha) dna-binding domain bound to its cognate response element

2000年11月29日 · Title: CRYSTAL STRUCTURE OF THE ORPHAN NUCLEAR RECEPTOR REV-ERB (ALPHA) DNA-BINDING DOMAIN BOUND TO ITS COGNATE RESPONSE ELEMENT. PDB DOI: https://doi.org/10.2210/pdb1ga5/pdb. Primary publication DOI: https://doi.org/10.1021/bi011086r. Entry authors: Sierk, M.L., Zhao, Q., Rastinejad, F. Initial deposition on: 29 November 2000.

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