人胚肺二倍体细胞2BS来自于女孩胚胎,1976年由北京生物制品研究所建株。 Cell aging of human diploid fibroblasts is associated with changes in responsiveness to epidermal growth factor and changes in HER-2 expression. The proliferative response and anti-oncogene expression in old 2BS cells after growth factor stimulation.

1995年4月21日 · We examined the proliferative response of 2BS cells of different population doubling levels to fibroblast growth factor (FGF). DNA synthesis was measured by thymidine incorporation. As the cells aged, there was a significant decrease in the stimulation of DNA synthesis by FGF addition (P < 0.01).

Establishment of a spontaneously transformed human fetal lung cell line and its biological characteristics. Cell aging of human diploid fibroblasts is associated with changes in …

E2F1 also induces Lsh protein expression and transactivates the Lsh promoter in 2BS cells. At the same time, E2F1-induced Lsh promoter activity is reduced in senescent cells compared to young cells.

MEM-EBSS培养基，80%；FBS，10%；水解蛋白，10%。 1：2至1：4，每周2次。 Cloning and characterization of cellular senescence-associated genes in human fibroblasts by suppression subtractive hybridization. The proliferative response and anti-oncogene expression in old 2BS cells after growth factor stimulation.

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