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The 340B Program enables covered entities to stretch scarce federal resources as far as possible, reaching more eligible patients and providing more comprehensive services. Manufacturers participating in Medicaid agree to provide outpatient drugs to covered entities at significantly reduced prices.

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Now Available: Price Detection/Bulk Exclusions Tool Check out the new price detection feature in 340B Architect! This tool allows you to review when a change in 340B pricing is identified for your pharmacies. Now you can act quickly and accurately to ensure maximum 340B savings. Learn more in the Help Guide.

Section 340B (a) (4) of the Public Health Service Act (PHS) Act (42 U.S.C. 256b) lists eligible organizations that can participate in and purchase discounted drugs under the 340B Program. HRSA's Office of Pharmacy Affairs (OPA) requires registration and approval for covered entities to participate in the 340B Program.

A person receiving 340B drugs must be a patient of the covered entity. However, unique circumstances may be considered to decide if an individual fits the definition of patient (PDF - 31 KB), and if they qualify to receive 340B drugs. A shortened health record may be enough for purposes of the 340B Drug Pricing Program.

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Participation in the 340B Program allows nonprofit healthcare organizations to receive outpatient drugs at significantly reduced prices. In order to participate in the 340B drug pricing program, organizations must register using 340B OPAIS. Registration occurs four times a year between the first and 15th days of January, April, July, and October.