4-Chloromethcathinone (also known as 4-CMC and clephedrone) is a stimulant drug of the cathinone class that has been sold online as a designer drug. [1] [2] 4-CMC produces similar effects to mephedrone, and has been sold as an alternative in countries where mephedrone was …

In summary, 4-CMC is one of the latest methcathinone derivatives to be sold and used in a similar manner as other licit and illicit stimulants. At the current time, there is evidence that 4-

2024年4月30日 · The estimation of the half-maximal inhibitory concentration (IC50) is critical for assessing the potential cardiotoxic effects of drug-like compounds such as 4-CMC. Specifically, it was found that a concentration of 240.2 µM of 4-CMC is required to achieve a 50% inhibition of hERG channel activity.

4-CMC (4-chloromethcathinone) is a synthetic cathinone with effects similar to those of other synthetic cathinones listed as Schedule II substances in the Convention on Psychotropic Substances of 1971.

The 4-chloromethcathinone (4-CMC) is a synthetic derivative of cathinone and belongs to new psychoactive substances. Neither data on the effects of 4-CMC on the human body, nor on nontoxic, toxic and lethal concentrations in biological materials have been published in …

Synthetic cathinones act as psychostimulants by elevating extracellular levels of monoaminergic neurotransmitters. This study investigates effects of 3-CMC, 4-CMC, 4-MeO-PVP, and 4-F-PVP on the spontaneous locomotor activity and motor performance of mice.

2024年6月11日 · SCs such as 3-methylmethcathinone (3-MMC), 3-chloromethylcathinone (3-CMC), and 4-CMC (clephedrone) constitute a large portion of total NPS seizures in the European drug market. Notably, in 2021, SC seizures represented more than 50% of the seized material, 3-CMC and 4-CMC accounting for 34 and 6%, respectively ( 1 , 2 ).

2024年6月11日 · Targeting metabolite markers is a go-to to document consumption in analytical toxicology, and metabolite profiling is crucial to support investigations. We sought to identify 3-CMC, 4-CMC, and 4-bromomethcathinone (4-BMC) human metabolites.

2015年8月5日 · 4-Chloromethcathinone (also referred to as clephedrone or 4-CMC) is one of many designer synthetic cathinones that has been sold on the illicit drug market.1 4-CMC is a derivative of US regulated Schedule I controlled substance methcathinone. The only difference between the two is that 4-CMC has a chlorine in the para position on the phenyl ring.

1-(4-chlorophenyl)-2-(methylamino)propan-1-one 1225843-86-6 4-CMC,para-chloro-N-methyl-cathinone, clephedrone DEAReference Material Collection White powder (HCl) Not Determined 2. CHEMICAL AND PHYSICAL DATA 2.1 CHEMICAL DATA Form Chemical Formula Molecular Weight Melting Point (oC) Base 198 Not Determined HCl C10H12ClNO. HCl 234 Not Determined ...