The condition 48,XXYY is not inherited; it usually occurs as a random event during the formation of reproductive cells (eggs and sperm). An error in cell division called nondisjunction results in a reproductive cell with an abnormal number of chromosomes. In 48,XXYY syndrome, the extra sex chromosomes almost always comes from a sperm cell ...

48,XXYY syndrome is a chromosomal condition that affects male development. There is a lot of variability in symptoms between people with 48,XXYY syndrome. Almost all affected individuals have developmental delays in infancy and develop decreased testosterone levels (hypogonadism) during adolescence.

48,XXYY syndrome is a chromosomal condition, characterized by the presence of an extra X and Y chromosome in males, that causes medical and behavioral problems. 48,XXYY can be considered a variant of Klinefelter syndrome.

48,XXYY is a sex chromosome variation that affects one in every 17,000 boys who are born.¹ XXYY Syndrome is the name attached to the cluster of symptoms that arise as a result of the 48,XXYY chromosome pattern.

2022年3月24日 · 48, XXYY is a genetic disorder that occurs in males and is characterized by additional sex chromosomes compared to the typical male karyotype of 46, XY. 48, XXYY syndrome has previously been described as a variant of Klinefelter syndrome because affected males have similar physical characteristics (tall stature and small, dysfunctional testes ...

48,XXYY syndrome results from a nondisjunction event of sex chromosomes during spermatogenesis or, less often, from post-zygotic mitotic nondisjunction during cell division. There are no known predisposing factors.

2023年11月14日 · 48, XXYY syndrome is a rare genetic condition, sometimes called double Y syndrome. Males are commonly affected. It is distinguished by an additional X and Y chromosome, giving rise to 48 instead of the typical 46 chromosomes.

48,XXYY syndrome is a chromosomal condition that affects male development. There is a lot of variability in symptoms between people with 48,XXYY syndrome. Almost all affected individuals have developmental delays in infancy and develop decreased testosterone levels (hypogonadism) during adolescence.

Our vision is a world where men and boys with XXYY Syndrome lead purposeful, productive lives. Read more about our mission. What is XXYY Syndrome? In support of our mission, the XXYY Project raises funds to further research on 48,XXYY Syndrome.

XXYY syndrome is a rare genetic disorder. Usually, a male will have one X chromosome and one Y chromosome , but people with this disorder have two of each. They have 48 chromosomes instead of the usual 46.