The 4Ts Score is a clinical scoring system to differentiate patients with HIT from those with other causes of thrombocytopenia.

6-8分，高度怀疑：抗体阴性者诊断HIT概率为16%，抗体阳性者诊断HIT概率为98%。 HIT 的4Ts评分诊断系统阴性预测值较高。 目前临床上先使用4T评分系统评价患者患HIT的可能性，如果高度或重度怀疑HIT，则应行相应实验室检查来确诊或排除HIT；如果只是低度怀疑，是否需要行实验室检查来明确或除外诊断尚无定论。 1. Lo GK et al. Evaluation of pretest clinical score (4T’s)for the diagnosis of heparin-induced thrombocytopenia in two clinical settings.J Thromb Haem 4 …

2024年5月14日 · The 4Ts in the 4T score are: - Thrombocytopaenia - Timing - Thrombosis - Other causes of Thrombocytopaenia are not evident.

4Ts评分是由血小板减少程度、减少时机、血栓形成和其他导致血小板减少原因4个要素构成，可将疑似患者分为低、中、高度临床可能性。 HIT抗体检测是现阶段唯一实现试剂商品化且可在普通实验室或床旁实施的试验方法。

The 4Ts (see Table 1) is a pretest scoring system for HIT that was developed to improve and standardize clinical diagnosis. It incorporates 4 typical features of HIT: (1) magnitude of thrombocytopenia; (2) timing of thrombocytopenia with respect to heparin exposure; (3) thrombosis or other sequelae of HIT; and (4) likelihood of other causes of ...

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2024年5月27日 · HIT type 1 — non-immunological. More common, with mild thrombocytopenia and a good prognosis. HIT type 2 — immunological. Rare, with severe thrombocytopenia and relatively worse outcome. Once we know what the 4 Ts of HIT score are, it's time to explain how to calculate the 4 T score.

2018年11月27日 · For patients who have a high-probability 4Ts score (89 of 1000 patients) and a positive immunoassay, continuing treatment with a non-heparin anticoagulant would mean a reduction in thrombosis, death, and amputation for 48 patients who have true HIT; however, for 6 patients without HIT, there is a short-term risk of bleeds (Table 4, strategy 4 ...

The 4Ts score is a means of stratifying risk of heparin-induced thrombocytopaenia syndrome (HITS), based on the onset and severity of thrombocytopaenia following heparin administration, as well as presence of features of HITS.

2022年5月26日 · Heparin-induced thrombocytopenia (HIT) is an adverse drug reaction to heparin that places patients at increased risk for venous or arterial thrombosis. HIT is generally suspected at the bedside when there is a characteristic 50% drop in platelet count following 5-10 days of heparin exposure, but other causes of thrombocytopenia must be considered.