5-MeO-DMT, also known as 5-methoxy- N, N -dimethyltryptamine, is a substituted tryptamine derivative. It is the 5- methoxylated derivative of N, N -dimethyltryptamine (DMT), the N, N - dimethylated derivative of 5-methoxytryptamine (5-MT; mexamine), and the O -methylated derivative of bufotenin (5-HO-DMT).

5-Methoxy-N,N-dimethyltryptamine (also known as 5-MeO-DMT) is a naturally-occurring psychedelic substance of the tryptamine class. It is structurally related to DMT and 5-HO-DMT ( bufotenin ) and is reputed to produce the most powerful and intense psychedelic states within the entire class. 5-MeO-DMT produces its effects by binding to serotonin ...

5‐MeO‐DMT is a fast‐acting tryptamine that can induce an immediate (within seconds) and intense psychedelic experience of short duration (10–20 min).

2024年8月3日 · 5-MeO-DMT, or 5-methoxy-dimethyltryptamine, is a naturally occurring tryptamine compound found in various plants and the venom of the Bufo alvarius toad, also known as the Colorado River toad or Sonoran Desert toad.

2025年1月15日 · 5-MeO-DMT (N,N-Dimethyl-5-methoxytryptamine) is a psychedelic tryptamine, 4 – 6 times stronger than the better-known DMT (N,N-dimethyltryptamine).

Synthetic, toad, and plant-sourced 5-MeO-DMT are used for spiritual and recreational purposes and may have psychotherapeutic effects. However, the use of 5-MeO-DMT is not well understood. Therefore, we examined patterns of use, motivations for consumption, subjective effects, and potential benefits and consequences associated with 5-MeO-DMT use.

Basics: 5-MeO-DMT is short for 5-methoxy-N,N-dimethyltryptamine. It’s found in several plants and in high concentrations in the secretion of the toad Bufo alvarius. It’s also possibly produced by the human body and has been found in human blood, urine, and cerebrospinal fluid.

5-MeO-DMT (5-methoxy dimethyltryptamine) is a psychoactive substance of the tryptamine class. The drug is believed to be the most intense psychedelic substance in the world. In fact, users say it is 10-20 times stronger than regular DMT . 5-MeO DMT comes from the Colorado River Toad (Bufo Alvarius) but can also be extracted from certain plants ...

5-meo-dmt 的个体剂量增加可靠地诱导“峰值”体验，这种状态被认为是迷幻药治疗效果的核心预测指标。观察性研究和调查表明，单次接触 5-meo-dmt 可导致抑郁、焦虑和压力症状的快速和持续减轻。

2023年12月11日 · 5-MeO-DMT is a tryptamine being developed as a potential antidepressant that may display a distinct therapeutic mechanism due to its unique pharmacology and subjective effects compared to typical psychedelics. In this article, we parallel the relatively distinct phenomenology and behavioral effects …