5-HT7 receptor - Wikipedia
The 5-HT7 receptor is a member of the GPCR superfamily of cell surface receptors and is activated by the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT). [5] .
HTR7 Gene - GeneCards | 5HT7R Protein | 5HT7R Antibody
2024年12月25日 · HTR7 (5-Hydroxytryptamine Receptor 7) is a Protein Coding gene. Diseases associated with HTR7 include Migraine With Or Without Aura 1 and Alcohol Dependence. …
5-HT7R通过促进CCR5泛素化增强神经免疫恢复力并缓解脑膜炎
2025年2月10日 · 本研究旨在探索5-HT7R和CCR5在细菌性脑膜炎中的相互作用机制，揭示血清素信号如何通过调控CCR5的表达来缓解感染引发的过度免疫反应和认知功能损伤，为神经免疫 …
Central nervous system effects of 5-HT
2022年6月20日 · In this review, we describe the signaling pathways and cellular mechanisms implicated in the activation of the 5-HT 7 R; also, we analyze different mechanisms of …
Structure–Activity Relationships and Therapeutic Potentials of 5 …
2018年5月16日 · Preclinical data link the 5-HT 7 R to a variety of central nervous system processes including the regulation of circadian rhythms, mood, cognition, pain processing, and …
5-HT7R enhances neuroimmune resilience and alleviates
Results: Fluoxetine, a selective serotonin reuptake inhibitor, or the agonist of serotonin receptor 5-HT 7 R, protects mice from meningitis by inhibiting CCR5-mediated excessive immune …
Role of 5-HT7 receptors in the immune system in health and …
2019年12月31日 · Serotonin effects are mediated through its interaction with 5-HT receptors (5-HTRs), a superfamily with a repertoire of at least fourteen well-characterized members. 5-HT 7 …
Discovery of β-Arrestin Biased Ligands of 5-HT 7 R - PubMed
2018年8月23日 · In an electroencephalogram (EEG) test, 1g increased total non-rapid eye movement (NREM) sleep time and decreased total rapid eye movement (REM) sleep time. …
The serotonin receptor 5-HT₇R regulates the morphology and
2015年8月1日 · Here, we demonstrate that expression of serotonin receptor 5-HT7 (5-HT7R) as well as its downstream effector Cdc42 is upregulated in dendritic cells upon maturation. …
The Importance of Stereochemistry in 5-HT - ACS Publications
Serotonin 5-HT 7 receptor (5-HT 7 R), one of the most recently discovered members of the serotonergic system, has become a promising target in the search for central nervous system …