Oct 2, 2018 · Neonatal thymocytes expressing T cell receptors that engage IA b -Padi4 with moderate dwell times within a conventional docking orientation are exported as tT reg cells. In contrast, Padi4-specific T cell receptors with short dwell times are expressed on CD4 + T cells, while long dwell times induce negative selection.

Preset Lines Axis Plane SelectionPDB : 6MNN

HEADER IMMUNE SYSTEM 02-OCT-18 6MNN TITLE 6236 TCR BOUND TO I-AB PADI4 COMPND MOL_ID: 1; COMPND 2 MOLECULE: H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN, A-B ALPHA CHAIN; COMPND 3 CHAIN: C; COMPND 4 SYNONYM: IAALPHA; COMPND 5 ENGINEERED: YES; COMPND 6 MOL_ID: 2; COMPND 7 MOLECULE: PADI4 (92-105) PEPTIDE AND MHC CLASS II I-AB BETA CHAIN; COMPND 8 ...

6236 TCR alpha chain6236 TCR beta chainH-2 class II histocompatibility antigen, A-B alpha chainPadi4 (92-105) peptide and MHC Class II I-Ab beta chain

>6MNN_1|Chain A[auth C]|H-2 class II histocompatibility antigen, A-B alpha chain|Mus musculus (10090) IEADHVGTYGISVYQSPGDIGQYTFEFDGDELFYVDLDKKETVWMLPEFGQLASFDPQGGLQNIAVVKHNLGVLTKRSNSTPATNEAPQATVFPKSPVLLGQPNTLICFVDNIFPPVINITWLRNSKSVADGVYETSFFVNRDYSFHKLSYLTFIPSDDDIYDCKVEHWGLEEPVLKHW

6mnn: 6236 tcr bound to i-ab padi4

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6mnn is a 4 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. HA2B_MOUSE.

Full wwPDB X-ray Structure Validation Report Oi May 17, 2020 04:05 am BST PDB ID : 6MNN Title : 6236 TCR bound to I-Ab Padi4 Authors : Blevins, S.J.; Stadinski, B.D.; Huseb,y E.S. Deposited on : 2018-10-02 Resolution : 2.83 Å(reported) This is a ullF wwPDB X-ray Structure alidationV Report for a publicly released PDB entry.

Initial deposition on: 2 October 2018 Initial release on: 3 July 2019