7SK RNA - Wikipedia
In molecular biology 7SK is an abundant small nuclear RNA found in metazoans. [1] It plays a role in regulating transcription by controlling the positive transcription elongation factor P-TEFb. [2] …
RN7SK Gene - GeneCards | RN7SK RNA Gene
2024年12月25日 · RN7SK (RNA Component Of 7SK Nuclear Ribonucleoprotein) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with RN7SK include …
7SK、U6和H1启动子 - 纽普生物
2024年8月2日 · 本文主要介绍三种3型pol iii启动子7sk、u6和h1启动子的序列、转录起始位点及它们的一些特点。 加粗部分为tata盒，绿色背景为+1位 人7sk 启动子:
上海交大张冰团队发现调控心肌线粒体合成和心力衰竭新机制_交大 …
2021年3月17日 · 以往研究认为7SK RNP的主要功能是阻止正转录延伸因子b（P-TEFb）与染色质和RNA聚合酶II（RNAPII）结合，进而抑制RNAPII ser2的磷酸化及其转录停滞释放（Pausing …
转录的延伸与暂停 - 知乎 - 知乎专栏
在人类细胞中，P-TEFb的非活性形式是与7SK snRNP结合的。P-TEFb可以被多种机制（Brd4、中介体或某些直接与DNA结合的激活剂）激活并募集到已暂停的Pol II复合物中。 磷酸化 …
7SK small nuclear RNA, a multifunctional transcriptional …
The 7SK small nuclear RNA is a multifunctional transcriptional regulatory RNA that controls the nuclear activity of the positive transcription elongation factor b (P-TEFb), specifically targets P …
N6-methyladenosine in 7SK small nuclear RNA underlies RNA …
2023年10月10日 · Human 7SK is an abundant and conserved 332-nucleotide small nuclear RNA (snRNA) that inhibits transcription elongation through negatively regulating P-TEFb kinase …
7SK small nuclear RNA, a multifunctional transcriptional ... - PubMed
The 7SK small nuclear RNA is a multifunctional transcriptional regulatory RNA that controls the nuclear activity of the positive transcription elongation factor b (P-TEFb), specifically targets P …
Interaction of 7SK with the Smn complex modulates snRNP production - Nature
2021年2月24日 · The noncoding RNA 7SK controls the transcription of mRNAs. Here, the authors show that the 7SK complex interacts with the Smn complex, suggesting crosstalk between …
Mol Cell：谢明艺团队揭示了核内小RNA 7SK 通过m6A修饰调控细 …
2023年10月10日，美国佛罗里达大学的谢明艺教授团队在Molecular Cell 杂志在线发表了题为“N6-methyladenosine in 7SK small nuclear RNA underlies RNA polymerase II transcription …