2018年3月1日 · After 60 min, iTLC results from the crude reaction showed better radiolabeling with the 89 Zr-(LT) (55%) than 89 Zr-(ST) (33%). FollowingPD-10 purification and …

2024年5月11日 · Production of 89 Zr, conjugation with the mostly used chelators and radiolabeling strategies, and quality control of the radiolabeled products are described in …

2024年9月1日 · In this work, we report on a suitable application of TK400 Resin to remove iron during [89 Zr]ZrCl 4 radiochemical isolation. The breakthrough allows for direct radiolabeling of …

89 Zr (t1/2 = 78.4 h), a positron-emitting metal, has been exploited for PET studies of antibodies because of its relatively long decay time and facile labeling procedures. Here, we used 89 Zr …

2020年11月1日 · Our results demonstrate that [89 Zr]Zr-oxine is a suitable PET alternative to [111 In]In-oxine for WBC imaging. Our formulation allows rapid, stable, high-yield, single-step …

2022年1月13日 · Clinical production of 89 Zr-radiolabeled antibodies (89 Zr-mAbs) for positron emission tomography imaging relies on the pre-conjugation of desferrioxamine B (DFO) to the …

In the present study, we determined that a lower concentration of H2C2O4 eluent (0.8M) is adequate to efficiently remove (89)Zr from a column containing 100mg hydroxamate resin. As …

使用 iTLC 和尺寸排阻色谱评估放射性偶联物的完整性。 这项研究表明，螯合剂和生物分子之间接头的性质会对 89 个 Zr 标记偶联物的稳定性以及偶联物的聚集产生重大影响。

2020年10月7日 · The photoradiochemical synthesis of purified 89Zr-mAbs, starting from unmodified proteins, [89Zr][Zr(C2O4)4]4– (89Zr-oxalate), and a photoactivatable DFO …

使用放射瞬时薄层色谱（iTLC）和放射高效液相色谱（放射高效液相色谱）来测定RCC。 细胞用[ 89 Zr]Zr-oxine 或[ 89 Zr]Zr-DFO-NCS标记。通过分析细胞功能，例如活力、增殖、吞噬能力和 …