2020年5月13日 · Here we report a novel large pericentric inversion of chromosome 9, inv (9) (p23q22.3) in several apparently unrelated carriers, resulting in fertility problems and abnormal offspring. We studied...

2013年4月1日 · Chromosome 9 presents the highest degree of morphological variations among the non-acrocentric human chromosomes. Variants include 9qh+, 9cenh+, 9ph+, 9qh-, or inv (9) (p11q13), and they are commonly found in routine cytogenetics, with an overall frequency of approximately 1.5% in the general population [1].

2005年7月1日 · The inv(9) in these patients may be a de novo inversion that cytogenetically mimics the constitutional inv(9) heteromorphism. Alternatively, it may be the result of neocentromere activation in 9q due to epigenetic events associated with the disease in these patients that results in a metacentric chromosome similarly mimicking the constitutional ...

Pericentric inversion 9 is a common chromosome variant with an incidence of approximately 1.6% in the general population [1]. Despite the relatively high incidence of this finding, there is debate in the literature over its clinical significance resulting in confusion about how to counsel patients regarding the medical management of this variant.

Here we report a novel large pericentric inversion of chromosome 9, inv(9)(p23q22.3) in several apparently unrelated carriers, resulting in fertility problems and abnormal offspring. We studied a...

One of the frequent occurrences in chromosome rearrangements is pericentric inversion of the Chromosome 9; inv (9) (p11q12), which is consider to be the variant of normal karyotype. Although it seems not to correlate with abnormal phenotypes, there ...

Pericentric inversion of the chromosome 9, inv (9) (p11q13), is such a common occurrence that some cytogeneticists would consider them as normal variants. The incidence is said to be about 1% to 1.65% in the general population.

2012年12月15日 · Here we present two sisters with a recombinant chromosome 9 due to a maternal pericentric inversion inv(9)(p24.3q34.1). The recombinant chromosome was further characterized by SNP array analysis and clinical features of both patients were compared to the previous four cases and with patients showing similar sized 9pter deletions or 9qter ...

2005年7月1日 · The inv(9) in these patients may be a de novo inversion that cytogenetically mimics the constitutional inv(9) heteromorphism. Alternatively, it may be the result of neocentromere activation in 9q due to epigenetic events associated with the disease in these patients that results in a metacentric chromosome similarly mimicking the constitutional ...

2020年5月1日 · Here we present a novel large pericentric inversion of chromosome 9, inv(9)(p23q22.3), detected in 30 heterozygote carriers, 24 from seven apparently unrelated families and 6 isolated patients ...