
YTH Domain: A Family of N6-methyladenosine (m6A) Readers
2018年4月1日 · The YTH domain represents a family that recognizes the m 6 A mark directly. By recruiting different complexes to target m 6 A sites, the YTH domain-containing proteins, as …
特别推荐 | 凡是过去,皆为序章——m6A结构生物学前沿进展 - 知乎
不仅如此,YTH domain上的一些氨基酸还可以与RNA上的其他碱基的相互作用,比如在YTH蛋白的识别过程中,YTHDC1更偏好在RNA的-1位置(甲基化的A为0号位)是G而不是A,因为G …
YTH protein domain - Wikipedia
In molecular biology, the protein domain YTH refers to a member of the YTH family that has been shown to selectively remove transcripts of meiosis-specific genes expressed in mitotic cells. …
CDD 综述︱杨祚璋团队综述了m6A阅读蛋白YTHDF1在多种人类肿 …
m6A结合蛋白通常包含YT521-B同源(YTH)结构域, YTH蛋白 是研究最深入的m6a结合蛋白,而大量研究发现 YT521-B同源结构域家族蛋白1(YTHDF1) 作为一种m6A结合蛋 …
A Unified Model for the Function of YTHDF Proteins in Regulating m
Our study reveals a unified model of m 6 A function in which all m 6 A-modified mRNAs are subjected to the combined action of YTHDF proteins in proportion to the number of m 6 A …
YTH Domain: A Family of N6-methyladenosine (m6A) Readers
Herein, we summarize the recent progresses made in understanding the molecular mechanisms underlying the m 6 A recognition by YTH domain-containing proteins, which would shed new …
Genome Biol︱芝加哥大学何川团队解析YTHDF家族蛋白功能的“不 …
YTHDF家族蛋白 (YTH N6-methyladenosine RNA binding proteins,包括YTHDF1、YTHDF2和YTHDF3) 是被研究最多的阅读器蛋白。在结合m6A修饰的RNA之后,YTHDF1可以提升翻译 …
YTH N6-甲基腺苷 RNA 结合蛋白 2(YTHDF2)基因 | MCE
yth 结构域是真核生物的典型结构域,在植物中尤为丰富。 yth 结构域通常位于蛋白质序列的中间,可能与 rna 结合。除了 yth 结构域外,该蛋白质还有一个可能参与信号转导的富含脯氨酸的 …
An m6A-YTH Module Controls Developmental Timing and ... - PubMed
YT521-B homology (YTH) domain proteins are important m 6 A readers with established functions in animals. Plants contain more YTH domain proteins than other eukaryotes, but their …
m 6 A阅读者YTH蛋白的研究进展 - zjnykx
yth蛋白是目前研究最为深入的m 6 a结合蛋白,本文从yth蛋白的分类、识别m 6 a的分子机理及其生物学功能3个方面详尽阐述了真核生物中存在的多样化的yth蛋白如何影响具有m 6 a修饰的rna …