Choukroun's platelet-rich fibrin (PRF) is obtained from blood without adding anticoagulants. In this study, protocols for standard platelet-rich fibrin (S-PRF) (2700 rpm, 12 minutes) and advanced platelet-rich fibrin (A-PRF) (1500 rpm, 14 minutes) were compared to …

Platelet-rich fibrin (PRF) represents second generation of platelet concentrates, which has gained increasing awareness in recent years for regenerative procedures. This biologic additive is completely autologous, easy to prepare, has minimal ...

Advanced platelet-rich fibrin is used clinically for various purposes related to reconstructive and jaw graft surgeries. Clinical studies have shown that A-PRF achieves satisfactory results for alveolar preservation after extractions, assisting in repair and minimizing bone resorption.

Objective: To determine whether leukocyte-platelet-rich fibrin (L-PRF) and advanced platelet-rich fibrin (A-PRF+) differ in their in vitro capacity to induce proliferation and migration of periodontal fibroblasts. Background: L-PRF and A-PRF + are autologous materials used in periodontal regenerative surgery.

2023年11月5日 · PRP （Platelet-Rich Plasma，富血小板血浆） 它是在1984年 Assoian 等报道的第一代自体富血小板血液制品，它的准备方法是通过向全血中添加抗凝剂，如氯化钙、凝血酶等化学物再通过离心从全血中分离出的高浓度血小板血浆。 由于富血小板血浆的制作和临床效果因需加入抗凝剂以及离心效果差而备受争议。 PRF （Platelet-RichFibrin，富血小板纤维蛋白） 它是 2000年报道的第二代富血小板血液制品，它的制备方法是通过全血不添加任何抗凝剂立刻一 …

Platelet-rich plasma and platelet-rich fibrin (PRF) are widely used in the field of stomatology. Advancements in preparation techniques and basic research have enabled the use of PRF derivatives in oral clinical applications.

2025年1月27日 · This study expands on the current literature by demonstrating the potential of A-PRF as an innovative drug delivery system. Unlike synthetic carriers, A-PRF is biocompatible, cost-effective, and derived from autologous sources, reducing the risk of immunogenic reactions.

摘要： 目的 观察改良型富血小板纤维蛋白（advanced- platelet-rich fibrin, A-PRF）对人骨髓间充质细胞（human bone marrow mesenchymal cells, hBMMCs）生物学性能的影响。 方法 对hBMMCs进行多向分化能力鉴定,扫描电镜及人生长因子阵列膜检测A-PRF微观结构及分子构成,CCK-8检测A-PRF对hBMMCs增殖的影响,划痕实验检测A-PRF对hBMMCs迁移的影响,通过碱性磷酸酶活性检测及茜素红染色检测不同浓度A-PRF对hBMMCs矿化能力的影响。

2023年12月29日 · Advanced platelet-rich fibrin is used clinically for various purposes related to reconstructive and jaw graft surgeries. Clinical studies have shown that A-PRF achieves satisfactory results for alveolar preservation after extractions, assisting in repair and minimizing bone resorption.

2014年12月1日 · The aim of the study was to assess histologically and histomorphometrically the cell distribution pattern of fibrin clots by applying the standard PRF (S-PRF) protocol with 12-minute centrifugation time and 2700 rpm as well as the new advanced PRF (A-PRF) protocol with 14-minute centrifugation time and 1500 rpm.