2023年6月10日 · In the current study, we investigated the expression of ANXA10 and p53 in biopsy and urine cytology samples for the first time, to our knowledge, and revealed that ANXA10 and p53 expression levels were weak or absent in benign cases, whereas high and strong nuclear expression was observed in UC cases.

2024年6月11日 · Transient TNF-α inhibition overcomes a p53-dependent program that restricts the survival of grafted dopamine neurons and offers a clinically relevant strategy to enhance survival and promote functional dopamine neuronal engraftment in cell-based therapies for Parkinson’s disease.

The authors previously reported that annexin A10 (ANXA10) expression was strongly linked to both papillary and early stage LGUC and was inversely correlated with p53 expression in upper tract UC (UTUC) and bladder UC. However, it remains largely unknown whether ANXA10 is useful as a diagnostic marker for urine cytology.

Antineoplaston A10 is an antineoplaston that inhibits the growth of human hepatoma cells by inducing apoptosis. Antineoplaston A10 can be used in the study of liver cancer and breast cancer.

2023年6月10日 · The authors previously reported that annexin A10 (ANXA10) expression was strongly linked to both papillary and early stage LGUC and was inversely correlated with p53 expression in upper tract UC (UTUC) and bladder UC. However, it remains largely unknown whether ANXA10 is useful as a diagnostic marker for urine cytology. Methods

研究结直肠癌组织中同源盒A10（HOXA10）和P53蛋白表达与临床病理特征及预后的关系。 收集2017年4月至2019年10月在西安市中心医院行手术治疗的97例结直肠癌患者的组织标本，采用免疫组织化学染色法检测癌组织及对应癌旁正常组织中HOXA10和P53蛋白表达情况。 分析HOXA10和P53蛋白表达与临床病理特征的关系；Spearman相关性分析结直肠癌组织中HOXA10和P53表达的相关性；Kaplan-Meier生存曲线分析HOXA10和P53蛋白表达与患者术后生存率的关系。 97例 …

Moreover, ANXA10 down-regulation and p53 mutation acted synergistically toward high-grade (P < 0.00001), high-stage HCC (P < 0.00001), and poorer prognosis (P = 0.0025). Our results indicate that the expression of the tissue- and tumor-restricted ANXA10 is a marker of liver cell differentiation and growth arrest, and its down-regulation ...

目的:研究结直肠癌组织中同源盒a10（hoxa10）和p53蛋白表达与临床病理特征及预后的关系。 方法:收集2017年4月至2019年10月在西安市中心医院行手术治疗的97例结直肠癌患者的组织标本，采用免疫组织化学染色法检测癌组织及对应癌旁正常组织中HOXA10和P53蛋白表达 ...

Our results indicate that the expression of the tissue- and tumor-restricted ANXA10 is a marker of liver cell differentiation and growth arrest, and its down-regulation associated with malignant phenotype of hepatocytes, vascular invasion, and progression of HCC, leading to poor prognosis.

2023年6月10日 · The authors previously reported that annexin A10 (ANXA10) expression was strongly linked to both papillary and early stage LGUC and was inversely correlated with p53 expression in upper tract UC (UTUC) and bladder UC. However, it remains largely unknown whether ANXA10 is useful as a diagnostic marker for urine cytology.