Current U.S. prevention guidelines for blood pressure and cholesterol management recommend use of the pooled cohort equations (PCE) to assess 10-year ASCVD risk and start a process of shared decision-making between clinicians and patients.

Determine 10-year risk of hard ASCVD, i.e. myocardial infarction, stroke, or death due to coronary heart disease or stroke. This calculator includes inputs based on race, which may or may not provide better estimates, so we have decided to make race optional. See here for more on our approach to addressing race and bias on MDCalc.

单年合同额 —— ACV （Annual Contract Value）：单年的签约合同金额，只包括1年的采购项金额。 因为多年合同中的一次性费用（若有）大部分发生在第一年，因此第一年的ACV时常高于后几年的ACV。

ASCVD stands for atherosclerotic cardiovascular disease, defined as a nonfatal myocardial infarction (heart attack), coronary heart disease death, or stroke. The purpose of the Pooled Cohort Equations is to estimate the risk of ASCVD within a 10-year period among patients who have never had one of these events in the past.

During the study, 10 episodes of ACV-resistant HSV occurred in cohort 1 and 2 episodes in cohorts 2 and 3 combined (P = .001). Conclusions: Long-term suppressive ACV prophylaxis sharply reduces the incidence of VZV disease during the first year after HCT with no detectable rebound disease after discontinuation of prophylaxis.

2020年9月2日 · Assessment of atherosclerotic cardiovascular disease (ASCVD) risk is crucial for prevention and management, but the performance of the pooled cohort equations in older adults with frailty and multimorbidity is unknown. We evaluated the pooled cohort equations in these subgroups and the impact of competing risks.

Methods: We compared 132 HSVE, 65 VZVE and 297 other IE enrolled in a prospective cohort (ENCEIF). We estimated associations between time-to-ACV start, dose or duration and outcome through adjusted odds ratio (aOR) using logistic regression analysis.

a Outcome and exposure association multipliers refer to values used in the OAC cohort/ACV cohort. From: Methods for Variable Selection and Treatment Effect Estimation in Nonrandomized Studies with Few Outcome Events and Many Confounders

Blunted cyclic variation of heart rate (CVHR), measured as a decrease in CVHR amplitude (Acv), predicts mortality risk after acute myocardial infarction (AMI). However, Acv also can be reduced in mild sleep apnea with mild O 2 desaturation. We investigated whether Acv's predictive power for post‐AMI mortality could be improved by considering ...

This Risk Estimator enables health care providers and patients to estimate 10-year and lifetime risks for atherosclerotic cardiovascular disease (ASCVD), defined as coronary death or nonfatal myocardial infarction, or fatal or nonfatal stroke, based on the Pooled Cohort Equations and lifetime risk prediction tools.