The “7+3” regimen in acute myeloid leukemia - PMC
2022年1月22日 · This breakthrough combination and schedule of drugs for AML, widely known as the “7 and 3” regimen, dramatically changed the prognosis of patients, has remained the …
A retrospective comparison of abbreviated course “7+7” vs …
2024年5月29日 · Background: Hypomethylating agent (HMA) plus venetoclax (VEN) regimens are standard of care in older/chemotherapy ineligible patients with acute myeloid leukemia (AML). …
Introduction to a How I Treat series on acute myeloid leukemia
6 天之前 · Treatment for patients with acute myeloid leukemia (AML) is being transformed for some patients, as targeted agents increase complete remission rates and s. ... were found to …
Optimizing Use of Newly Approved Agents for Acute Myeloid Leukemia
2019年10月8日 · Since the 1970s, the historical standard of care regimen for fit patients with acute myeloid leukemia (AML) was 7 continuous days of cytarabine and 3 days of an …
Novel Agents for Acute Myeloid Leukemia - PMC - National …
2018年11月9日 · In this review, we will present and describe these recently approved drugs as well as selected novel agents against AML that are currently under investigation, and show the …
AML treatment: conventional chemotherapy and emerging novel agents …
2024年5月1日 · In this review, we provide a general synopsis of current treatments of AML, new targeted agents, and potential future therapies. We focus upon the synthesis of these …
Emerging agents and regimens for AML - BioMed Central
2021年3月23日 · Until recently, acute myeloid leukemia (AML) patients used to have limited treatment options, depending solely on cytarabine + anthracycline (7 + 3) intensive …
Mayo Genetic Risk Models for Newly Diagnosed Acute Myeloid Leukemia ...
2024年12月13日 · Patients with newly diagnosed acute myeloid leukemia (ND-AML) derive variable survival benefit from venetoclax + hypomethylating agent (Ven-HMA) therapy. The …
Frontiers | Identifying acute myeloid leukemia subtypes based on ...
6 天之前 · The AML subtypes display different pathway and biological process enrichment. In the TCGA-LAML dataset, we identified nine gene modules by WGCNA (Langfelder and Horvath, …
A retrospective comparison of abbreviated course “7+7” vs …
2024年6月1日 · The “7+7” regimen was associated with lower platelet transfusion requirements and lower 8-week mortality and a signal for a difference in efficacy between standard VEN …