RUNX1 - Wikipedia
Runt-related transcription factor 1 (RUNX1) also known as acute myeloid leukemia 1 protein (AML1) or core-binding factor subunit alpha-2 (CBFA2) and it is a protein that is encoded by …
The AML1 gene: a transcription factor involved in the
AML1 encodes a nuclear transcription factor (TF) which shows homology in its 5' part with the Drosophila melanogaster segmentation gene, runt, and contains a transactivation domain in …
【科普贴】AML1-ETO的前世今生 - 丁香园论坛 - DXY.cn
aml1-eto是在wnt/β这个东西诱导下使得8，21染色体易位形成的；又叫作runx1-runx1t1 形成的AML1-ETO长这样，相应片段可以和下面黑色mRNA或者蛋白质作用； 最常见的两种形式
AML1/ETO and its function as a regulator of gene transcription via ...
2021年7月30日 · In this review, we will focus on recent results highlighting the role of AML1/ETO as an epigenetic modifier, which provides a strong rationale to treat the disease with so-called …
Cancer Res：北京协和医院王敏等团队研究表明靶向脂肪酸代谢消 …
2024年12月26日 · aml1–eto是急性髓性白血病（aml）中最常见的融合蛋白之一，由runx1::runx1t1融合基因编码，能够生成前白血病克隆。 2024年12月16日，中国医学科学院北 …
RUNX1 Gene - GeneCards | RUNX1 Protein | RUNX1 Antibody
2024年12月25日 · Isoform AML-1G shows higher binding activities for target genes and binds TCR-beta-E2 and RAG-1 target site with threefold higher affinity than other isoforms. It is less …
AML1 Antibody #4334 - Cell Signaling Technology (CST)
AML1 antibody detects endogenous levels of total AML1 protein and the AML1/ETO fusion protein. Human, Monkey. Polyclonal antibodies are produced by immunizing animals with a …
Definition of a small core transcriptional circuit regulated by AML1 ...
2021年2月4日 · Transcription factors regulate gene networks controlling normal hematopoiesis and are frequently deregulated in acute myeloid leukemia (AML). Critical to our understanding …
伴AML1-ETO融合基因的急性髓系白血病患者ASXL2基因突变及临 …
探讨伴AML1-ETO融合基因的急性髓系白血病（AML）患者ASXL2基因突变情况、突变阳性患者临床特征及ASXL2基因突变与c-kit基因突变的关系。 采用PCR扩增产物片段直接测序分析法， …
AML1/RUNX1 functions as a cytoplasmic attenuator of NF-κB …
2011年12月15日 · Transcription factor AML1/RUNX1 is one of the most frequent targets of chromosomal abnormalities in human leukemia and altered function of AML1 is closely …