
ANGPTL4 - Wikipedia
ANGPTL4, specifically the C-terminal fragment (cANGPTL4), is a key player that coordinates an increase in cellular energy flux crucial for epithelial-mesenchymal transition (EMT) via an …
ANGPTL4 Gene - GeneCards | ANGL4 Protein | ANGL4 Antibody
2024年12月24日 · ANGPTL4 (Angiopoietin Like 4) is a Protein Coding gene. Diseases associated with ANGPTL4 include Plasma Triglyceride Level Quantitative Trait Locus and Familial …
新一代降脂药物靶点-ANGPTLs - 知乎 - 知乎专栏
angptl3/8复合物分泌入血,可抑制循环系统、以及氧化组织(如心脏、肌肉)中的lpl活性。喂食状态下,angptl8上调(angptl4下调),使得心脏和肌肉中的lpl活性受angptl3/8抑制,进而使得 …
ANGPTL4, A MULTIFUNCTIONAL PROTEIN INVOLVED IN …
ANGPTL4 is a secreted glycoprotein with a physiological role in lipid metabolism and a predominant expression in adipose tissue and liver. ANGPTL4 inhibits the activity of …
Suppression of angiopoietin-like 4 reprograms endothelial cell
2023年12月12日 · Here, using endothelial-specific Angptl4 knock-out mice (Angptl4iΔEC), and transcriptomics and metabolic flux analysis, we demonstrate that ANGPTL4 is required for …
ANGPTL4的作用及机制-SciEngine
血管生成素样蛋白4(angiopoietin-like 4,ANGPTL4)是血管生成素家族的一员。作为多功能分泌蛋白,ANGPTL4能抑制脂蛋白脂肪酶的活性,在脂质代谢中发挥重要生理作用。
血管生成素样蛋白4与心力衰竭的相关研究进展 - 中华心力衰竭和 …
血管生成素样蛋白4(angptl4)是主要在肝脏及脂肪组织表达的一种脂肪因子,属于血管生成素样蛋白家族。angptl4通过影响血管生成、炎症等参与体内多种生理过程。
ANGPTL4—A protein involved in glucose metabolism, lipid …
2024年10月28日 · In this review, we provide an overview of the fundamental role of ANGPTL4 in metabolic regulation and its impact on tumor growth. These insights may provide a way for …
糖尿病肾病新靶点:耶鲁大学发现肾脏Angptl4的重要作用
2024年12月4日,美国耶鲁大学医学院Julie E. Goodwin教授团队在期刊《Science Advances》上发表了题为“Renal Angptl4 is a key fibrogenic molecule in progressive diabetic kidney …
Role and mechanism of the action of angiopoietin-like protein ANGPTL4 ...
2021年1月1日 · ANGPTL4 is a fasting- and lipid-induced factor secreted by numerous cells, including adipocytes, hepatocytes, (cardio)myocytes, and macrophages. In adipocytes, …