2023年2月4日 · Methods: In this pragmatic, open-label, non-inferiority trial in 15 hospitals in the Netherlands, patients with complex appendicitis (aged ≥8 years) were randomly assigned (1:1) …

2020年10月5日 · We conducted the Comparison of Outcomes of Antibiotic Drugs and Appendectomy (CODA) trial to compare antibiotic therapy with appendectomy in adults with …

2023年2月4日 · The antibiotics following appendicectomy in complex appendicitis (APPIC) trial was designed to compare a 2-day regimen of intravenous postoperative antibiotics with a 5 …

2018年5月2日 · In patients with a complex appendicitis, prolonged antibiotic prophylaxis is recommended after appendectomy. There is no consensus regarding the optimum duration of …

To compare costs for 2 days versus 5 days of postoperative antibiotics within the antibiotics after an aPPendectomy In Complex appendicitis trial. Background: Recent studies suggest that …

In patients aged ≥ 8 years with complex appendicitis, short 2-day course was noninferior to standard 5-day course with respect to the rate of infectious complications and death within 90 …

2023年2月4日 · In this pragmatic, open-label, non-inferiority trial in 15 hospitals in the Netherlands, patients with complex appendicitis (aged ≥8 years) were randomly assigned (1:1) …

2018年5月2日 · The Antibiotics following aPPendectomy In Complex appendicitis (APPIC) trial is a phase IV, prospective, multicenter, non-blinded, randomized controlled trial powered for non …

Methods: In this pragmatic, open-label, non-inferiority trial in 15 hospitals in the Netherlands, patients with complex appendicitis (aged ≥8 years) were randomly assigned (1:1) to receive 2 …

To our knowledge, this is the first adequately powered level I randomised controlled trial that evaluates the safety and eficacy of postoperative antibiotics restricted to 2 days. This trial …