2023年3月27日 · As a class, angiotensin receptor blockers, or ARBs, bind to and inhibit the angiotensin II type 1 receptor and are indicated to treat hypertension, congestive heart failure, and diabetic nephropathy. They are often used as an ACE inhibitor therapy replacement for patients who cannot tolerate ACE inhibitors because of the ACE inhibitor-induced ...

The appearance of angiotensin receptor blockers (ARBs) amongst the therapeutic options in the treatment of cardiovascular diseases (CVDs) was a new milestone in the history of hypertension treatment. It further widened the range of possibilities for personalized therapy, especially for patients who cannot tolerate the use of angiotensin ...

Angiotensin receptor blockers (also called ARBs or angiotensin II inhibitors) are medicines that dilate (widen) blood vessels, and are used in the treatment of conditions such as high blood pressure (hypertension), heart failure, or kidney disease in people with diabetes. ARBs work by blocking the action of a natural chemical called angiotensin II.

Angiotensin II receptor blockers or ARBs are an effective treatment for high blood pressure, heart failure, kidney disease and other conditions. The medications prevent angiotensin II proteins from binding to receptors in the blood which causes blood vessels to narrow.

All national guidelines for the management of hypertension recommend angiotensin receptor blockers (ARBs) as an initial or add-on antihypertensive therapy. The 8 available ARBs have variable clinical efficacy when used for control of hypertension.

2023年8月4日 · Angiotensin 2 receptor blockers stop the action of angiotensin 2. As a result, the medicine helps relax the veins and arteries in the body, lowering blood pressure. Several angiotensin 2 receptor blockers are available. Which one is best for you depends on your health and the condition being treated.

Start with a low dose of angiotensin-II receptor blocker (ARB) and titrate upwards every 4 weeks until the target blood pressure has been achieved, or the person has reached the maximum prescribable or tolerated dose of ARB.

2021年7月26日 · ACE (angiotensin-converting enzyme) inhibitors and angiotensin receptor blockers (ARBs) are equally guideline-recommended first-line treatments for hypertension, yet few head-to-head studies exist. We compared the real-world effectiveness and safety of ACE inhibitors versus ARBs in the first-line treatment of hypertension.

The new study in the LEGEND-HTN series is the largest head-to-head comparison of ACE inhibitors and ARBs to date. It included data from almost 3 million patients with hypertension who began first-line treatment with 1 of the drug classes between 1996 and 2018.

Angiotensin II receptor blockers (ARBs), formally angiotensin II receptor type 1 (AT 1) antagonists, [1] also known as angiotensin receptor blockers, [2] [3] angiotensin II receptor antagonists, or AT 1 receptor antagonists, are a group of pharmaceuticals that bind to and inhibit the angiotensin II receptor type 1 (AT 1) and thereby block the ...