SUN13837 in Treatment of Acute Spinal Cord Injury, the ASCENT-ASCI Study
2017年12月23日 · In a 26-week, double-blind trial, 65 subjects were randomized (1:1) by stratum within 12 hours of injury to 1 mg/kg/day of intravenous SUN13837 (SUN) or matching placebo …
Serum S100-Beta as a Biomarker for Neurological Recovery in …
2025年2月18日 · Background: Acute spinal cord injury (ASCI) leads to severe neurological deficits with limited prognostic biomarkers. However, S100-beta (S100B), a calcium-binding protein, …
The safety and efficacy of steroid treatment for acute spinal …
2020年2月1日 · The present study demonstrated no statistically significant improvement in motor or neurological recovery among patients treated with methylprednisolone in the first 8-hour …
Duraplasty in acute spinal cord injury: a systematic review
1 天前 · Background Acute spinal cord injury (aSCI) can cause severe, lasting disabilities that may be fatal. Expansile duraplasty has been explored as a potential intervention aimed at …
The potential role of heat shock proteins in acute spinal
2014年2月6日 · This study aims to investigate the differential expression proteins profile of spinal cord tissues after acute spinal cord injury (ASCI), provide preliminary results for further study …
The current role of steroids in acute spinal cord injury
Background: Acute spinal cord injury (ASCI) is a catastrophic event that can profoundly affect the trajectory of a patient's life. Debate continues over the pharmacologic management of ASCI, …
American Society of Clinical Investigators (ASCI)
The assay is utilized to study the antioxidant properties of plant extracts and their role in stress resistance and adaptation . Biomedical Research Antioxidants play a crucial role in protecting …
Serum S100-Beta as a Biomarker for Neurological Recovery in
2025年2月18日 · This study highlights the promising role of serum S100B as a crucial biomarker for assessing both the severity of ASCI and the subsequent recovery process. The fluctuations …
Current status of clinical trials for acute spinal cord injury
2005年7月1日 · Acute spinal cord injury (ASCI) occurs as a result of physical disruption of spinal cord axons through the epicenter of injury leading to deficits in motor, sensory, and autonomic …
The protective mechanism of action of plantamajoside on a rat …
Acute spinal cord injury (ASCI) is a severe traumatic disease of the central nervous system, characterized by a high incidence and high morbidity, for which there are no effective drug …