2024年5月10日 · Adjunctive ATG (equine) therapy successfully reverses most initial episodes of acute rejection in renal allograft recipients, including a high percentage of episodes severe …

Atgam, ATG equine (antithymocyte globulin equine) dosing, indications, interactions, adverse effects, and more. Range: 10-30 mg/kg IV qDay. Delaying onset of rejection (start within 24 hours of...

ATGAM is an immunoglobulin G indicated for: For intravenous use only. ATGAM 50 mg/mL concentrate for solution for infusion. (3) Anaphylactic reaction during prior administration of ATGAM or any other equine gamma globulin preparation. (4) Anaphylaxis, which can be life-threatening, has been reported.

2023年9月20日 · Atgam is a polyclonal antibody, or an immune globulin, given as an intravenous (IV, into a vein) infusion. Atgam is used to fight a type of white blood cell called a T-lymphocyte (also called a thymocyte or T-cell). T-lymphocytes are part of your immune system.

MDS治疗推荐方案是根据病人的修订版国际预后评分系统（R-IPSS）评分和患者的体力（PS）与分子基因检测，如5q-31缺失。 目前，美国FDA批准治疗MDS的药物仅少数几个。 来那度胺（lenalidomide）、低甲基化药物（hypomethylating agents HMA）如阿扎胞苷（azacitidine）和地西他滨（decitabine），以及铁螯合剂如地拉罗司（deferasirox）。 这些患者可接受支持治疗。 最初可能会观察到一些不需要输血且有中度无症状的细胞减少的患者。

2014年12月6日 · Our experience suggests that low dose ATGAM at 15mg/kg/day D1-5 as treatment of AA produces similar responses and outcomes as per standard dose ATGAM scheduling. Prospective trials comparing ATGAM dose schedules in AA are warranted.

2017年12月7日 · Introduction: It is generally known that horse antithymocytic globulin (ATGAM) are more effective for treatment of pts with acquired AA than rabbit ATG. There is no doubt, that dose regime 160 mg/kg ATGAM Improves response for young pts after 1 st course.

Anti-Thymocyte Globulin [Equine] IV infusion 40mg/kg/day on day 1- 4 (for 4 days). Allow 5 working days to acquire stock of Equine ATG from manufacturer. For obese patients, the dose must be calculated according to ideal body weight.

2014年6月7日 · 40mg/kg/d，连用 4 天，对于年轻的低危或中危-1，其骨髓呈低增生或正常增生型的 MDS患者。 30%患者产生疗效，Hb 上升而停止输血。

The purpose of this study was to determine the efficacy of and tolerance to antithymocyte globulin (ATG)-based therapy in patients with myelodysplastic syndrome (MDS). Therapy consisted of ATG 40 mg/kg/day daily intravenously (i.v.) for 4 days; cyclosporine daily orally for 6 …