Acute renal failure, now referred to as acute kidney injury, is a common and clinically important problem. Acute kidney injury frequently occurs as a result of acute tubular necrosis (ATN), which ...

DAMPs in ATN. Neutralization of the DAMP HMGB1 with a monoclonal antibody was shown to attenuate renal injury after ischemia-reperfusion injury (IRI), while recombinant HMGB1 exacerbates it ...

2011年12月5日 · Activation of the sympathetic nervous system results in renal vasoconstriction and reduced renal blood flow, leading to progressive renal failure, reduced glomerular filtration, and even ATN. 1 2 ...

2004年12月2日 · Typically, urine sodium is < 10 mmol/L in HRS and > 20 mmol/L in ATN due to impaired reabsorption of sodium from damaged renal tubules, but this feature is not always reliable. Heme-granular casts ...

2023年12月11日 · Of course, vancomycin is known to cause interstitial renal disease and certainly can cause problems with higher doses. So if using in combination, you might see somewhat higher serum creatinine ...

ATN is a common cause of DGF, but there are others: ... urinary and/or vascular obstruction are ruled out as causes of ATN, a second renal biopsy may be necessary to make a definitive diagnosis.

2005年7月11日 · A randomized trial has shown no difference in clinical outcomes, including acute renal failure, in cardiac-surgery patients treated with either fenoldopam or dopamine. A separate report shows ...

2014年8月19日 · For the current study, they examined 5 databases for medical information on 97,777 adults aged 65 years or older (mean age, 80.7 years) who lived in Ontario, Canada, and who received a new ...

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2022年4月1日 · Acute kidney injury is a known complication in patients receiving immunotherapy, but the reported incidence in clinical trials is only 2%-3% of patients. A higher incidence (up to 17%) has been ...