Acute renal failure, now referred to as acute kidney injury, is a common and clinically important problem. Acute kidney injury frequently occurs as a result of acute tubular necrosis (ATN), …

DAMPs in ATN. Neutralization of the DAMP HMGB1 with a monoclonal antibody was shown to attenuate renal injury after ischemia-reperfusion injury (IRI), while recombinant HMGB1 …

2011年12月5日 · Activation of the sympathetic nervous system results in renal vasoconstriction and reduced renal blood flow, leading to progressive renal failure, reduced glomerular …

2004年12月2日 · Typically, urine sodium is < 10 mmol/L in HRS and > 20 mmol/L in ATN due to impaired reabsorption of sodium from damaged renal tubules, but this feature is not always …

2023年12月11日 · Of course, vancomycin is known to cause interstitial renal disease and certainly can cause problems with higher doses. So if using in combination, you might see …

ATN is a common cause of DGF, but there are others: ... urinary and/or vascular obstruction are ruled out as causes of ATN, a second renal biopsy may be necessary to make a definitive …

2005年7月11日 · A randomized trial has shown no difference in clinical outcomes, including acute renal failure, in cardiac-surgery patients treated with either fenoldopam or dopamine. A …

2014年8月19日 · For the current study, they examined 5 databases for medical information on 97,777 adults aged 65 years or older (mean age, 80.7 years) who lived in Ontario, Canada, …

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2022年4月1日 · Acute kidney injury is a known complication in patients receiving immunotherapy, but the reported incidence in clinical trials is only 2%-3% of patients. A higher incidence (up to …