Aptamer-based ATP-responsive delivery systems for cancer diagnosis …
2021年3月15日 · Aptamers possess unique properties including, ligand-specific response, short sequence (~ 20-80 bases) and easy functionalization. Thus, their combination with ATP …
Pushing Adenosine and ATP SELEX for DNA Aptamers with …
2023年3月22日 · The classical DNA aptamer for adenosine and ATP has been the most used small molecule binding aptamer for biosensing, imaging, and DNA nanotechnology. This …
高亲和力的腺苷和ATP适体的筛选、表征及应用- X-MOL资讯
2023年4月16日 · 腺苷和三磷酸腺苷（ATP）的经典DNA适体（aptamer）在生物传感、成像和DNA纳米技术等领域应用广泛。 该适体序列最早由Szostak课题组于1995年报道，且在之后的 …
Redox-Switchable Binding Properties of the ATP–Aptamer
2019年9月3日 · In this study, we report on a redox-controllable and reversible complete “ON”/“OFF”-switchable aptamer binding to ATP. A series of methylene blue-modified …
G-Quadruplex Structure in the ATP-Binding DNA Aptamer …
2024年3月15日 · In this paper, we explored adenosine triphosphate (ATP)-binding aptamers for the simultaneous detection of two small-molecule ligands: adenosine triphosphate (ATP) and …
Rational design of aptamer switches with programmable pH response - Nature
2020年6月10日 · From a single ATP aptamer, we engineer pH-controlled target binding under diverse conditions, achieving pH-induced selectivity in affinity of up to 1,000-fold. Importantly, …
Thermodynamic analysis of cooperative ligand binding by the ATP …
2020年11月3日 · We have used isothermal titration calorimetry methods to study the binding of ATP, ADP, AMP and adenosine to the ATP-binding aptamer. Using both individual and global …
Modular Engineering of Aptamer‐Based Nanobiotechnology for …
2023年11月27日 · This review focuses on the modular engineering of regulatable sensing technology via the integration of aptamer probe designs with advanced functional …
DNA tetrahedron-based split aptamer probes for reliable imaging of ATP ...
2023年3月1日 · Here, we developed a DNA tetrahedron-based split aptamer probe (TD probe) for ratiometric fluorescence imaging of ATP in living cells. The TD probe is constructed by …
ATP detection using a label-free DNA aptamer and a cationic ...
A simple and sensitive method for ATP detection using a label-free DNA aptamer as the recognition element and ethidium bromide (EB) as the signal reporter is reported. The ATP …