2021年3月22日 · What is a lipid disorder? A lipid disorder will typically increase levels of LDLs, triglycerides, or both. HDLs are known as good cholesterol because they help to transport bad cholesterol out...

2016年8月23日 · Lipid metabolism disorders, such as Gaucher disease and Tay-Sachs disease, involve lipids. Lipids are fats or fat-like substances. They include oils, fatty acids, waxes, and cholesterol. If you have one of these disorders, you may not …

Abnormal levels of blood lipids cause fat deposits in artery walls, which initiates complications inside the blood vessels. Causes for high lipid levels include diabetes, alcoholism, kidney disease, hypothyroidism, liver disease, and stress.

The main disorders of lipid metabolism are LDL-hypercholesterolemia, hypertriglyceridemia, mixed hyperlipoproteinemia, and low HDL cholesterol. The lipoprotein (a) level can also be elevated either in isolation or in combination with other disorders of lipid metabolism.

Lipids are fats that are either absorbed from food or synthesized by the liver. Triglycerides (TGs) and cholesterol contribute most to disease, although all lipids are physiologically important. Cholesterol is a ubiquitous constituent of cell membranes, steroids, bile …

2024年8月2日 · Recent research has linked abnormalities in lipid metabolism to the onset and progression of the disease. Additionally, pathological studies have revealed that ectopic adipose tissue surrounds the β cells in the pancreatic islets, exacerbating the …

Disorders that affect lipid metabolism may be caused by defects in the structural proteins of lipoprotein particles, in the cell receptors that recognize the various types of lipoproteins, or in the enzymes that break down fats.

2024年8月2日 · Therefore, we discuss the processes of aberrant lipid metabolism in various human diseases in this review, including diseases of the cardiovascular system, neurodegenerative diseases, endocrine system diseases (such as obesity and type 2 diabetes mellitus), and other diseases including cancer.

Lipid metabolism disorder is a physiopathological event characterized by the abnormal synthesis, breakdown, digestion, absorption and transport of lipids in the body, resulting in excessive or insufficient lipids in various tissues and thus affecting body functions.

2016年9月27日 · As evidenced, abnormal lipid metabolism is associated with type 2 diabetes mellitus, obstructive sleep apnea, coronary artery disease, nonalcoholic fatty liver diseases, cancer, etc. [3, 4]. Much research has been conducted to reveal the essential roles of lipid metabolism in energy homeostasis and metabolic diseases.