
Acetylcholinesterase at the neuromuscular junction
2020年9月14日 · Acetylcholinesterase (AChE) is an essential enzymatic component of the neuromuscular junction where it is responsible for terminating neurotransmission by the cholinergic motor neurons.
Acetylcholinesterase Inhibitors: Pharmacology and Toxicology
Acetylcholinesterase (AChE, acetycholine acetylhydrolase, E.C. 3.1.1.7) is found in many types of conducting tissue: nerve and muscle, central and peripheral tissues, motor and sensory fibers, and cholinergic and noncholinergic fibers. The activity of AChE is higher in motor neurons than in sensory neurons [1-3]. AChE is also found in the red ...
Acetylcholinesterase - Wikipedia
Acetylcholinesterase (HGNC symbol ACHE; EC 3.1.1.7; systematic name acetylcholine acetylhydrolase), also known as AChE, AChase or acetylhydrolase, is the primary cholinesterase in the body. It is an enzyme that catalyzes the breakdown of acetylcholine and some other choline esters that function as neurotransmitters :
Physiology, Acetylcholinesterase - StatPearls - NCBI Bookshelf
2023年1月19日 · Acetylcholinesterase (AChE) is a cholinergic enzyme primarily found at postsynaptic neuromuscular junctions, especially in muscles and nerves. It immediately breaks down or hydrolyzes acetylcholine (ACh), a naturally …
Acetylcholinesterase at the neuromuscular junction
2020年9月14日 · Acetylcholinesterase (AChE) is an essential enzymatic component of the neuromuscular junction where it is responsible for terminating neurotransmission by the cholinergic motor neurons.
Acetylcholinesterase: From 3D Structure to Function - PMC
By rapid hydrolysis of the neurotransmitter, acetylcholine, acetylcholinesterase terminates neurotransmission at cholinergic synapses. Acetylcholinesterase is a very fast enzyme, functioning at a rate approaching that of a diffusion-controlled ...
Acetylcholinesterase - an overview | ScienceDirect Topics
Acetylcholinesterase (AChE) is a serine protease degrades acetylcholine between cholinergic synapses and terminates cholinergic neural signaling (Silman and Sussman 2008). Studies have revealed that AChE activity was reduced in PD patients with cognitive impairment, and the loss of cholinergic was observed within the central and peripheral ...
Acetylcholinesterase - SpringerLink
2018年1月1日 · Acetylcholinesterase is a serine hydrolase that cleaves choline esters rapidly, preferentially acetylcholine (ACh). AChE shows a great ACh-hydrolyzing capacity, and in the list of enzymes classified according to their catalytic efficiency AChE occupies the second position.
Molecule of the Month: Acetylcholinesterase - RCSB: PDB-101
Acetylcholinesterase is found in the synapse between nerve cells and muscle cells. It waits patiently and springs into action soon after a signal is passed, breaking down the acetylcholine into its two component parts, acetic acid and choline.
Physiology, Acetylcholinesterase - PubMed
2023年1月19日 · Acetylcholinesterase (AChE) is a cholinergic enzyme primarily found at postsynaptic neuromuscular junctions, especially in muscles and nerves. It immediately breaks down or hydrolyzes acetylcholine (ACh), a naturally …